Evidence map›Paper›PMID 40330753›Full record

ReviewHealth science reports2025

Exercise Training Modalities in Young and Middle-Aged Adults With Prehypertension or Hypertension: A Systematic Review and Network Meta-Analysis.

Lu Tian, Siyu Yang, Yulan Hu, Jinrui Cui, Xiaobei Guo, Zongfeng Liao, Yu Liu

Abstract readReview
In one paragraph

Review in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lu TianNursing Department Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology Wuhan Hubei P.R. China.ORCID 0009-0003-1885-0337
Siyu YangNursing Department Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology Wuhan Hubei P.R. China.
Yulan HuNursing Department Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology Wuhan Hubei P.R. China.
Jinrui CuiNursing Department Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology Wuhan Hubei P.R. China.
Xiaobei GuoNursing Department Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology Wuhan Hubei P.R. China.
Zongfeng LiaoNursing Department Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology Wuhan Hubei P.R. China.
Yu LiuNursing Department Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology Wuhan Hubei P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: The question of how to choose the right type of exercise to lower blood pressure and cardiovascular risk factors in people worldwide with high blood pressure is not yet fully understood. Thus, the aim of this study was to investigate the effects of various exercise training on blood pressure and cardiovascular risk factors among young and middle-aged adults with prehypertension or hypertension. Design: Systematic review and network meta-analysis. Methods: We searched five electronic databases to identify randomized controlled trials that compare exercise training versus a sedentary or sham control group in young and middle-aged adults with prehypertension or hypertension. Review Manager 5.3, Stata15.0, and R4.2.1 software estimated the efficacy of exercise training modalities. Results: We included 19 eligible articles with 1590 participants to assess five exercise trainings. Our findings indicated that low-middle intensity aerobic exercise (mean difference (MD) = -8.08, 95% confidence interval (CI) = -13.58, -2.58) was superior to all exercise strategies (high-intensity aerobic exercise: MD = -6.53, 95% CI = -12.51, -0.56; high-intensity resistance exercise: MD = -4.95, 95% CI = -11.07, 1.17; low-middle-intensity resistance exercise: MD = -3.49, 95% CI = -12.36, 5.39) compared with control group in lowering systolic blood pressure. Compared with the control strategy, high-intensity resistance exercise (MD = -4.75, 95% CI = -8.00, -1.50), high-intensity aerobic exercise (MD = -4.27, 95% CI = -7.08, -1.45) could lower diastolic blood pressure. The effects of different exercise patterns on cardiovascular risk factors, the results indicated that only low-middle-intensity aerobic exercise significantly improved body mass index (MD = -0.55, 95% CI = -7.08, -1.45), total cholesterol (MD = -19.07, 95% CI = -36.42, -1.72), triglycerides (MD = -14.32, 95% CI = -23.16, -5.48), high-density lipoprotein (MD = 2.29, 95% CI = 0.85, 3.73), and low-density lipoprotein (MD = -13.90, 95% CI = -22.18, -5.63). In addition, no intervention affects heart rate. Conclusion: Compared with other types of exercise, aerobic exercise can significantly improve systolic blood pressure, while high-intensity resistance or aerobic exercise may significantly improve diastolic blood pressure. In addition, AE-LM is effective in the reduction of risk factors that are contributors to the development of cardiovascular disease. Therefore, this study provides strong evidence to support the selection of appropriate exercise modalities for hypertensive patients.

Indexed as

exercise traininghypertensionmiddle‐agenetwork meta‐analysisprehypertensionyoung

Identifiers

PMID40330753
PMCPMC12054716

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.