Evidence map›Paper›PMID 40331589›Full record

ArticleAmerican journal of physiology. Lung cellular and molecular physiology2025

Store-operated Ca

Aleksandra Babicheva, Ibrahim Elmadbouh, Shanshan Song, Michael A Thompson, Ryan Powers, Pritesh P Jain, Amin Izadi, Jiyuan Chen, Lauren Yung, Sophia Parmisano and 12 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Lung cellular and molecular physiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

22 authors.

Aleksandra BabichevaThe Hormel Institute, University of Minnesota, Austin, Minnesota, United States.ORCID 0000-0002-0152-2121
Ibrahim ElmadbouhThe Hormel Institute, University of Minnesota, Austin, Minnesota, United States.ORCID 0000-0001-8892-124X
Shanshan SongDepartment of Medicine, University of California, San Diego, La Jolla, California, United States.
Michael A ThompsonDepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota, United States.
Ryan PowersDepartment of Medicine, University of California, San Diego, La Jolla, California, United States.
Pritesh P JainDepartment of Medicine, University of California, San Diego, La Jolla, California, United States.
Amin IzadiDepartment of Medicine, University of California, San Diego, La Jolla, California, United States.
Jiyuan ChenDepartment of Medicine, University of California, San Diego, La Jolla, California, United States.
Lauren YungDepartment of Medicine, University of California, San Diego, La Jolla, California, United States.
Sophia ParmisanoDepartment of Medicine, University of California, San Diego, La Jolla, California, United States.ORCID 0000-0002-4054-9546
Cole PaquinDepartment of Medicine, University of California, San Diego, La Jolla, California, United States.
Wei-Ting WangDepartment of Medicine, University of California, San Diego, La Jolla, California, United States.
Yuqin ChenDepartment of Medicine, University of California, San Diego, La Jolla, California, United States.
Ting WangDepartment of Medicine, University of California, San Diego, La Jolla, California, United States.
Mona AlotaibiDepartment of Medicine, University of California, San Diego, La Jolla, California, United States.
John Y-J ShyyDepartment of Medicine, University of California, San Diego, La Jolla, California, United States.ORCID 0000-0002-5625-753X
Patricia A ThistlethwaiteDepartment of Surgery, University of California, San Diego, La Jolla, California, United States.
Jian WangDepartment of Medicine, University of California, San Diego, La Jolla, California, United States.
Ayako MakinoDepartment of Medicine, University of California, San Diego, La Jolla, California, United States.ORCID 0000-0003-1259-8604
Y S PrakashDepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota, United States.ORCID 0000-0002-2968-224X
Christina M PabelickDepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota, United States.ORCID 0000-0002-4632-2174
Jason X-J YuanDepartment of Medicine, University of California, San Diego, La Jolla, California, United States.ORCID 0000-0002-0685-4862

Funding

Ion Channels and Membrane Receptors in Pulmonary Arterial HypertensionR35HL135807 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI YUAN, JASON X J · 2017 to 2023
$5.6M
Ion Channels and Membrane Receptors in Pulmonary Arterial HypertensionR35HL171538 · NHLBI · UNIVERSITY OF FLORIDA · PI Jason X J Yuan · 2024 to 2026
$3.8M
American Heart Association (AHA) 20POST35210959American Heart Association (AHA) 25IAUST1363304American Heart Association-American Stroke Association 20POST35210959 - ALEKSANDRA BABICHEVAAmerican Heart Association-American Stroke Association 25IAUST1363304HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) HL135807Minnesota Partnership for Biotechnology and Medical Genomics MNP #24.04NHLBI NIH HHS R35 HL135807NHLBI NIH HHS R35 HL171538UMN Hormel Institute Eagles Telethon Postdoctoral FellowshipUMN Hormel Institute Transformative Ideas Program
6 · The paper itself

Abstract

Endothelial-to-mesenchymal transition (EndMT) is a biological process that converts endothelial cells to mesenchymal cells with increased proliferative and migrative abilities. EndMT has been implicated in the development of pulmonary vascular remodeling in pulmonary arterial hypertension (PAH), a fatal and progressive lung vascular disease. Transforming growth factor β

Indexed as

CalciumCalcium SignalingEndothelial CellsEndothelium, VascularEpithelial-Mesenchymal TransitionLungCells, CulturedHumansNeoplasm ProteinsORAI1 ProteinSnail Family Transcription FactorsStromal Interaction Molecule 1Transforming Growth Factor beta1CalciumNeoplasm ProteinsORAI1 ProteinORAI1 protein, humanSNAI1 protein, humanSnail Family Transcription FactorsSTIM1 protein, humanStromal Interaction Molecule 1Transforming Growth Factor beta1Ca2+ signalingendothelial-to-mesenchymal transitionpulmonary hypertensionSTIM/Oraistore-operated Ca2+ channels

Identifiers

PMID40331589
PMCPMC12169631

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.