ArticleChemical research in toxicology2025
Identification and Structural Elucidation of a Novel Pyrrolidinophenone-Based Designer Drug on the Illicit Market: α-BPVP.
Article in Chemical research in toxicology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The identification of a new psychoactive substances (NPS) with a cathinone structure and a biphenyl substituent, found in seized powder from the black market, is here reported. By combining analytical techniques, including 1D and 2D NMR and HRMS, the compound was identified as 1-([1,1'-biphenyl]-4-yl)-2-(pyrrolidin-1-yl)pentan-1-one (α-BPVP), an α-pyrrolidinopentiophenone (α-PVP) analogue featuring a biphenyl group instead of the phenyl ring. This previously unreported molecule raises urgent legal and public health concerns, which warrants further toxicological investigation.
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