Evidence map›Paper›PMID 40331997›Full record

ArticleInternational journal of molecular sciences2025

Phenotypic and Genotypic Bacterial Virulence and Resistance Profiles in Hidradenitis Suppurativa.

Corina Ioana Cucu, Călin Giurcăneanu, Elena Poenaru, Liliana Gabriela Popa, Mircea Ioan Popa, Mariana Carmen Chifiriuc, Veronica Lazăr, Alina Maria Holban, Irina Gheorghe-Barbu, Andrei-Alexandru Muntean and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. The Pathogenicity Mechanisms ofInternational journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Corina Ioana CucuDepartment of Oncologic Dermatology, "Elias" Emergency University Hospital, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.ORCID 0000-0002-3097-846X
Călin GiurcăneanuDepartment of Oncologic Dermatology, "Elias" Emergency University Hospital, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Elena PoenaruDepartment of Medical Informatics and Biostatistics, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.ORCID 0000-0002-6414-0841
Liliana Gabriela PopaDepartment of Oncologic Dermatology, "Elias" Emergency University Hospital, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.ORCID 0000-0002-1702-7280
Mircea Ioan PopaDepartment of Microbiology II, "Cantacuzino" Institute, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.ORCID 0000-0002-0794-9329
Mariana Carmen ChifiriucResearch Institute of the University of Bucharest-ICUB, University of Bucharest, 050663 Bucharest, Romania.ORCID 0000-0001-6098-1857
Veronica LazărResearch Institute of the University of Bucharest-ICUB, University of Bucharest, 050663 Bucharest, Romania.
Alina Maria HolbanResearch Institute of the University of Bucharest-ICUB, University of Bucharest, 050663 Bucharest, Romania.
Irina Gheorghe-BarbuResearch Institute of the University of Bucharest-ICUB, University of Bucharest, 050663 Bucharest, Romania.
Andrei-Alexandru MunteanDepartment of Microbiology II, "Cantacuzino" Institute, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.ORCID 0000-0002-4124-2909
Costin Ștefan CaracotiDepartment of Microbiology II, "Cantacuzino" Institute, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.ORCID 0000-0002-3867-9122
Mara Mădălina MihaiDepartment of Oncologic Dermatology, "Elias" Emergency University Hospital, "Carol Davila" University of Medicine and Pharmacy, 020021 Bucharest, Romania.ORCID 0000-0002-1436-0088

Funding

Unitatea Executiva Pentru Finantarea Invatamantului Superior a Cercetarii Dezvoltarii si Inovarii PN-III-P1-1.1-PD-2019-1225
6 · The paper itself

Abstract

Hidradenitis suppurativa (HS) is a chronic inflammatory skin condition, primarily affecting young individuals, with a significant impact on their quality of life due to recurrent, painful nodules, abscesses, and oozing sinus tracts, primarily affecting intertriginous areas. The pathogenesis of HS is multifactorial, involving a complex interplay between genetic predisposition, immune dysregulation, microbial, and environmental factors. While it is known that cutaneous and gut microbiome contribute to innate immune dysregulation in HS, their precise involvement in disease pathogenesis remains unclear. Despite several studies investigating the microbiome of HS lesions, either by culture-dependent or independent methods, there is no data available on the interplay between bacterial virulence profiles, clinical manifestations, and the host immune response. This study aimed to explore the phenotypic and genotypic resistance and virulence profiles of microorganisms isolated from HS lesions (including the expression of soluble virulence factors and the ability to develop biofilms), with a special focus on

Indexed as

Drug Resistance, BacterialHidradenitis SuppurativaAdultAnti-Bacterial AgentsBiofilmsFemaleGenotypeHumansMalePhenotypeStaphylococcus aureusVirulenceVirulence FactorsAnti-Bacterial AgentsVirulence Factorsbiofilmhidradenitis suppurativaskin microbiomeStaphylococcus aureusvirulence factors

Identifiers

PMID40331997
PMCPMC12026681

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.