Evidence map›Paper›PMID 40332525›Full record

ArticleInternational journal of molecular sciences2025

Sialyllactose Attenuates Inflammation and Injury of Intestinal Epithelial Cells upon Enterotoxigenic

Qiming Duan, Bing Yu, Zhiqing Huang, Yuheng Luo, Ping Zheng, Xiangbing Mao, Jie Yu, Junqiu Luo, Hui Yan, Jun He

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Effects of Chlorogenic Acid-RichAntioxidants (Basel, Switzerland) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Qiming DuanInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.
Bing YuInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.ORCID 0000-0001-6605-6742
Zhiqing HuangInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.ORCID 0000-0001-5092-9297
Yuheng LuoInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.
Ping ZhengInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.
Xiangbing MaoInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.ORCID 0000-0002-6292-7747
Jie YuInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.ORCID 0000-0002-8486-1611
Junqiu LuoInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.
Hui YanInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.ORCID 0000-0001-7476-3914
Jun HeInstitute of Animal Nutrition, Sichuan Agricultural University, Chengdu 611130, China.ORCID 0000-0002-1963-9766

Funding

Innovation Team of Sichuan Province SCCXTD-2024-8National Natural Science Foundation of China 32372897
6 · The paper itself

Abstract

Sialyllactose (SL), a bioactive trisaccharide abundant in porcine colostrum, demonstrates multifunctional properties including antimicrobial activity, immune regulation, and apoptosis inhibition. This research uncovers the mechanisms by which SL mitigates enterotoxigenic

Indexed as

Enterotoxigenic Escherichia coliEpithelial CellsEscherichia coli InfectionsInflammationIntestinal MucosaLactoseAnimalsBacterial AdhesionCell LineNF-kappa BSignal TransductionSwineTight JunctionsToll-Like Receptor 4LactoseNF-kappa BToll-Like Receptor 4Escherichia coliinflammatory injuryIPEC-J2 cellslipopolysaccharideNF-κBsialyllactose

Identifiers

PMID40332525
PMCPMC12027521

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.