Evidence map›Paper›PMID 40332613›Full record

ArticleInternational journal of molecular sciences2025

Whole-Genome Sequencing Unveils the Uniqueness of Yushu Yaks (

Bao Cai, Xiaoyun Wu, Yilin Shi, Yandong Kang, Ziqiang Ding, Shaoke Guo, Mengli Cao, Liyan Hu, Ben Zhang, Xingdong Wang and 5 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Bao CaiKey Laboratory of Yak Breeding of Gansu Province, Lanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences, Lanzhou 730050, China.ORCID 0009-0005-6844-9191
Xiaoyun WuKey Laboratory of Yak Breeding of Gansu Province, Lanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences, Lanzhou 730050, China.
Yilin ShiKey Laboratory of Yak Breeding of Gansu Province, Lanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences, Lanzhou 730050, China.ORCID 0009-0009-6045-6564
Yandong KangKey Laboratory of Yak Breeding of Gansu Province, Lanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences, Lanzhou 730050, China.ORCID 0000-0001-8844-3321
Ziqiang DingKey Laboratory of Yak Breeding of Gansu Province, Lanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences, Lanzhou 730050, China.
Shaoke GuoKey Laboratory of Yak Breeding of Gansu Province, Lanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences, Lanzhou 730050, China.
Mengli CaoKey Laboratory of Yak Breeding of Gansu Province, Lanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences, Lanzhou 730050, China.
Liyan HuKey Laboratory of Yak Breeding of Gansu Province, Lanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences, Lanzhou 730050, China.ORCID 0000-0001-6197-419X
Ben ZhangKey Laboratory of Yak Breeding of Gansu Province, Lanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences, Lanzhou 730050, China.ORCID 0009-0003-6066-2962
Xingdong WangKey Laboratory of Yak Breeding of Gansu Province, Lanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences, Lanzhou 730050, China.ORCID 0000-0002-6008-4731
Jie PeiKey Laboratory of Yak Breeding of Gansu Province, Lanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences, Lanzhou 730050, China.ORCID 0000-0001-7726-3077
Qianyun GeKey Laboratory of Yak Breeding of Gansu Province, Lanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences, Lanzhou 730050, China.
Lin XiongKey Laboratory of Yak Breeding of Gansu Province, Lanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences, Lanzhou 730050, China.
Songshan ZhangBeijing Institute of Animal Husbandry and Veterinary Medicine, Chinese Academy of Agricultural Sciences, Beijing 100080, China.
Xian GuoKey Laboratory of Yak Breeding of Gansu Province, Lanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences, Lanzhou 730050, China.ORCID 0000-0003-2390-4777

Funding

China Agriculture Research System of MOF and MARA CARS-37Innovation Project of Chinese Academy of Agricultural Sciences (25-LZIHPS-01)the National Key Research and Development Program of China 2022YFD1602303
6 · The paper itself

Abstract

The Yushu yak is one of China's distinctive yak breeds, primarily distributed in the Yushu Tibetan Autonomous Prefecture of Qinghai Province and its surrounding areas. Yushu yaks are not only economically and culturally significant but also play a crucial role in protecting the ecosystem of the Qinghai-Tibet Plateau and promoting sustainable development. However, there are no clear records regarding the ancestry, population structure, and unique traits of Yushu yaks. Therefore, this study conducted an analysis of genetic diversity, population structure, and selection signals in Yushu yak populations, aiming to provide references for the conservation and utilization of the breed genetic resources. The results of the analysis showed that the Yushu yak population has high genetic diversity and low inbreeding coefficients, indicating a stable genetic structure. Population structure analysis revealed that the Yushu yak lineage is unique, with limited gene flow between domestic and wild yaks. Functional enrichment analysis of positively selected genes in Yushu yaks indicated prominent selection features related to growth and development as well as energy metabolism. Additionally, we classified the Yushu yak breeding bulls into family lineages based on kinship, which is essential for improving the efficiency of utilizing genetic resources and scientifically managing the population.

Indexed as

Whole Genome SequencingAnimalsBreedingCattleChinaGene FlowGenetics, PopulationGenetic VariationGenomeMalePhylogenyPolymorphism, Single Nucleotidepopulation structureselection signalswhole-genome resequencingYushu yak

Identifiers

PMID40332613
PMCPMC12027638

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.