ArticleJournal of assisted reproduction and genetics2025
Case report: re-biopsy rescues a to-be-discarded segmental aneuploid embryo resulting in a healthy pregnancy with normal prenatal testing results.
Article in Journal of assisted reproduction and genetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- Misdiagnosis of different types of aneuploidy in preimplantation genetic testing (PGT): a systematic review and meta-analysis.Archives of gynecology and obstetrics · 2026Pooled it
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This case report describes the strategy for reclassifying embryos initially diagnosed as segmental aneuploid through preimplantation genetic testing for aneuploidy (PGT-A), potentially rescuing those embryos for clinical use. A couple undergoing IVF, facing a lack of viable embryos, opted to re-biopsy a previously tested uniform (non-mosaic) segmental aneuploid embryo. The repeat PGT-A analysis produced a euploid result. Following thorough consultation with a genetic counselor and the treating physician, and after signing an informed consent detailing the associated risks, the couple proceeded with the embryo transfer. The pregnancy was confirmed, and prenatal testing by amniocentesis produced euploid results. This case highlights the potential of re-biopsy to more accurately assess embryos initially diagnosed as segmental aneuploid, helping to avoid the unnecessary discard of viable embryos while minimizing the clinical risks associated with constitutive segmental aneuploidies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.