ArticlePathogens (Basel, Switzerland)2025
Albaconazole Polymeric Nanocapsules for Treating
Cristina Maria de Barros, Vanja Maria Veloso, Margareth Spangler Andrade, José Mário Carneiro Vilela, Maria Alice de Oliveira, Marta de Lana, Maria Terezinha Bahia, Vanessa Carla Furtado Mosqueira
Abstract read
In one paragraphArticle in Pathogens (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
8 authors.
Cristina Maria de BarrosLaboratory of Pharmaceutics and Nanotechnology, School of Pharmacy, Federal University of Ouro Preto, Campus Universitário Morro do Cruzeiro, Ouro Preto 35400-000, MG, Brazil.
Vanja Maria VelosoDepartment of Pharmacy, School of Pharmacy, Federal University of Ouro Preto, Ouro Preto 35400-000, MG, Brazil.
Margareth Spangler AndradeLaboratory of Nanoscopy, FIEMG SENAI Technological Center-Regional Department of Minas Gerais, Belo Horizonte 31035-536, MG, Brazil.
José Mário Carneiro VilelaLaboratory of Nanoscopy, FIEMG SENAI Technological Center-Regional Department of Minas Gerais, Belo Horizonte 31035-536, MG, Brazil.
Maria Alice de OliveiraLaboratory of Pharmaceutics and Nanotechnology, School of Pharmacy, Federal University of Ouro Preto, Campus Universitário Morro do Cruzeiro, Ouro Preto 35400-000, MG, Brazil.
Marta de LanaPost-Graduation Program in Biological Sciences (NUPEB), Exact and Biological Sciences Institute (ICEB), Federal University of Ouro Preto, Ouro Preto 35400-000, MG, Brazil.ORCID 0000-0002-1565-4707 Maria Terezinha BahiaPost-Graduation Program in Biological Sciences (NUPEB), Exact and Biological Sciences Institute (ICEB), Federal University of Ouro Preto, Ouro Preto 35400-000, MG, Brazil.
Vanessa Carla Furtado MosqueiraLaboratory of Pharmaceutics and Nanotechnology, School of Pharmacy, Federal University of Ouro Preto, Campus Universitário Morro do Cruzeiro, Ouro Preto 35400-000, MG, Brazil.ORCID 0000-0002-0368-6090 Funding
World Health Organization ID A00790
6 · The paper itselfAbstract
The therapeutic management of Chagas disease requires new medicines because the standard-of-care drugs available induce adverse effects and have limited efficacy. In this study, we developed a formulation of albaconazole (ABZ) loaded in biodegradable polymeric nanocapsules (NCs). Free ABZ and ABZ-loaded NCs were similarly active against the Y strain and inactive against the Colombian strain epimastigotes of
Indexed as
Chagas DiseaseNanocapsulesTrypanocidal AgentsTrypanosoma cruziAnimalsDisease Models, AnimalFemaleMiceParasitemiaPolymersNanocapsulesPolymersTrypanocidal Agentsalbaconazoledosage regimendose–responseefficacyformulationnanoparticlestoxicityUR-9825
Identifiers
PMID40333049
PMCPMC12030734
What Socratic holds
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LicenceCC BY
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