Evidence map›Paper›PMID 40333073›Full record

ArticlePathogens (Basel, Switzerland)2025

Kharon Is Crucial for

Jose Luis Saenz-Garcia, Normanda Souza-Melo, Juliana Severo Miranda, Beatriz Borges, Lisandro A Pacheco-Lugo, Jose M Quintero-Solano, Nilmar Moretti, Richard Wheeler, Lia C Soares-Medeiros, Wanderson D DaRocha

Abstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jose Luis Saenz-GarciaLaboratório de Genômica Funcional de Parasitos (GFP), Universidade Federal de Paraná, Curitiba 81531-980, Brazil.
Normanda Souza-MeloLaboratório de Ultraestrutura Hertha Mayer, Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro 21491-590, Brazil.ORCID 0000-0003-2025-1088
Juliana Severo MirandaLaboratório de Genômica Funcional de Parasitos (GFP), Universidade Federal de Paraná, Curitiba 81531-980, Brazil.
Beatriz BorgesLaboratório de Biologia Celular, Instituto Carlos Chagas, Fundação Oswaldo Cruz (Fiocruz), Curitiba 81310-020, Brazil.ORCID 0000-0002-2195-1273
Lisandro A Pacheco-LugoFacultad de Ciencias Básicas y Biomédicas, Universidad Simón Bolívar, Barranquilla 080020, Colombia.ORCID 0000-0002-9248-4596
Jose M Quintero-SolanoLaboratorio de Biotecnología Farmacéutica, Centro de Biotecnología Genόmica, Instituto Politécnico Nacional, Reynosa 88710, Mexico.ORCID 0009-0006-5729-3344
Nilmar MorettiLaboratório de Biologia Molecular de Patógenos (LBMP), Departamento de Microbiologia, Imunologia e Parasitologia, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo 04023-062, Brazil.ORCID 0000-0003-0455-2497
Richard WheelerNuffield Department of Medicine, University of Oxford, Oxford OX1 3SY, UK.
Lia C Soares-MedeirosLaboratório de Biologia Celular, Instituto Carlos Chagas, Fundação Oswaldo Cruz (Fiocruz), Curitiba 81310-020, Brazil.ORCID 0000-0001-9390-9157
Wanderson D DaRochaLaboratório de Genômica Funcional de Parasitos (GFP), Universidade Federal de Paraná, Curitiba 81531-980, Brazil.

Funding

FAPESP 2018/09948-0FAPESP 2020/07870-4FAPESP 2022/03075-0Fundação Araucária 2020221000012
6 · The paper itself

Abstract

Chagas disease, caused by

Indexed as

Chagas DiseaseProtozoan ProteinsTrypanosoma cruziAnimalsCRISPR-Cas SystemsCytoskeletonProtozoan ProteinsCRISPR/Cas9morphologyTrypanosoma cruzi

Identifiers

PMID40333073
PMCPMC12030701

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.