Evidence map›Paper›PMID 40333396›Full record

ReviewMaterials (Basel, Switzerland)2025

The Recent Developments of Thermomechanical Processing for Biomedical Mg Alloys and Their Clinical Applications.

Hui Zhao, Jing Cheng, Chaochao Zhao, Min Wen, Rui Wang, Di Wu, Zhaoying Wu, Fang Yang, Liyuan Sheng

Abstract readReview
In one paragraph

Review in Materials (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hui ZhaoSchool of Material Science and Engineering, Xi'an Shiyou University, Xi'an 710065, China.ORCID 0000-0002-9350-2848
Jing ChengSchool of Material Science and Engineering, Xi'an Shiyou University, Xi'an 710065, China.
Chaochao ZhaoShenzhen Institute, Peking University, Shenzhen 518057, China.
Min WenPKU-HKUST ShenZhen-HongKong Institution, Shenzhen 518057, China.
Rui WangPKU-HKUST ShenZhen-HongKong Institution, Shenzhen 518057, China.
Di WuShenzhen Institute, Peking University, Shenzhen 518057, China.
Zhaoying WuSchool of Biomedical Engineering, Shenzhen Campus, Sun Yat-Sen University, Shenzhen 518107, China.ORCID 0000-0003-2410-3752
Fang YangPKU-HKUST ShenZhen-HongKong Institution, Shenzhen 518057, China.ORCID 0009-0008-5512-3776
Liyuan ShengPKU-HKUST ShenZhen-HongKong Institution, Shenzhen 518057, China.ORCID 0000-0001-7729-0315

Funding

National Natural Science Foundation of China 52127801Shenzhen Basic Research Projects JCYJ20220531091802006 and JCYJ20210324120001003Xi'an Science and Technology Plan Program 24GXFW0073
6 · The paper itself

Abstract

Magnesium (Mg) alloys have gained much attention for biomedical applications, due to their attractive properties, such as high specific strength, low density, low elasticity modulus, high damping capacity, biodegradation, and relatively good cytocompatibility. However, the biomedical use of Mg alloys also faces several challenges, primarily due to their low corrosion resistance and insufficient strength. Therefore, improving the strength and corrosion resistance of biomedical Mg alloys has become a critical issue. This review briefly summarizes the selection of appropriate alloying elements for biomedical Mg alloys, which is the fundamental factor in determining their microstructure, cytocompatibility, mechanical properties, and corrosion performance. It also discusses typical thermomechanical processing methods, including hot extrusion, hot rolling and hot forging, and examines the influence of deformation mode on microstructure, mechanical properties, and degradation behavior. Specifically, combining different thermomechanical processing methods could be an optimal choice, as it leverages the high efficiency and effectiveness of each method. Finally, the clinical application of biomedical Mg alloys in various fields are summarized and discussed to highlight their potential prospect and corresponding challenges. This review aims to provide insights for the rationale design and development of high-performance biomedical Mg alloys for widespread clinical applications.

Indexed as

biomedical Mg alloyclinical applicationcorrosion ratecytocompatibilitymechanical propertiesmicrostructurethermomechanical processing

Identifiers

PMID40333396
PMCPMC12028547

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.