ArticleApplied clinical informatics2025
Academic Detailing to Enhance Adoption of Clinical Decision Support for Patients at Risk of Opioid Overdose.
Article in Applied clinical informatics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Leveraging the 72-Hour Rule Change to Support Transition From Hospital to Opioid Treatment Program.JAMA network open · 2025Article
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNot all patients at risk for opioid overdose are prescribed naloxone when discharged from the emergency department or hospital. Clinical decision support (CDS) can be used to promote clinical best practices, such as naloxone prescribing; however, it may be ignored due to knowledge deficiencies or alert fatigue.
objectivesAssess the effect of academic detailing on responses to a CDS alert recommending a naloxone prescription for patients at risk of opioid overdose.
methodsA pre/postquality improvement study of 2,161 active providers at a 400-bed academic medical center. The first intervention was an educational email to all providers. The second intervention was individual emails to 150 providers who infrequently ordered naloxone in response to the alert. The main outcome measure was prescription-to-alert ratios, defined as the number of naloxone prescriptions signed in response to the alert divided by the number of times the alert fired.
resultsThe first academic detailing intervention resulted in a prescription-to-alert ratio increase from 32.6 to 51.7%, a 19.1% absolute increase when comparing the approximately 8 months before and after the email was sent (95% confidence interval [CI]: 16.3-21.9%,
conclusionAcademic detailing can be used to augment responses to CDS for patients with opioid dependence. Further study is needed to see if this effect can be replicated with CDS for other high priority conditions, and whether academic detailing with one alert might improve responses to other alerts as well, potentially decreasing alert fatigue.
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