Evidence map›Paper›PMID 40334740›Full record

SynthesisThe Journal of pediatrics2025

Accuracy of Home Blood Pressure Monitoring in Youth: A Systematic Review and Meta-Analysis.

Victoria Cueto, Hugh Medvecky, Melissa C Funaro, James T Nugent

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in The Journal of pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Hypertension: Evaluation and Management.Indian journal of pediatrics · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Victoria CuetoSection of General Pediatrics, Department of Pediatrics, Yale School of Medicine, New Haven, CT.
Hugh MedveckyYale Center for Clinical Investigation, Yale School of Medicine, New Haven, CT.
Melissa C FunaroHarvey Cushing/John Hay Whitney Medical Library, Yale School of Medicine, New Haven, CT.
James T NugentSection of General Pediatrics, Department of Pediatrics, Yale School of Medicine, New Haven, CT; Section of Pediatric Nephrology, Department of Pediatrics, Yale School of Medicine, New Haven, CT; Clinical and Translational Research Accelerator, Department of Medicine, Yale School of Medicine, New Haven, CT. Electronic address: james.nugent@yale.edu.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Guideline-Recommended Implementation of Pediatric Ambulatory Blood Pressure Monitoring (GRIP ABPM)K23HL177261 · NHLBI · YALE UNIVERSITY · PI James Nugent · 2025 to 2026
$390k
NCATS NIH HHS UL1 TR001863NHLBI NIH HHS K23 HL177261
6 · The paper itself

Abstract

objectiveTo evaluate the accuracy of home blood pressure monitoring (HBPM) in youth compared with the reference standard of ambulatory BP monitoring (ABPM). STUDY

designMEDLINE, Embase, Web of Science, and Cochrane Library were systematically searched from inception to November 13, 2024. Two authors identified studies testing the accuracy of HBPM compared with ABPM in youth ≤18 years. We assessed outcomes on the continuous scale (mean difference [MD]) or categorical scale (sensitivity, specificity, κ). We conducted a meta-analysis using hierarchical random effects weights.

resultsOf the 2966 titles screened, 26 studies were included (total n = 1992 patients, median 59 per study). Daytime home BP was lower than awake ambulatory BP (systolic MD, -6.4 mmHg [95% CI, -10.7 to -2.0]; diastolic MD, -3.3 mmHg [95% CI, -6.0 to -0.7]). Diagnosing daytime ambulatory hypertension by HBPM had modest sensitivity (0.52-0.64) and good specificity (0.82-0.97), with moderate agreement (κ 0.50-0.65). Accuracy was higher for white coat hypertension (sensitivity, 0.77-0.89; specificity, 0.85-0.94; κ, 0.66-0.73) and specificity was slightly higher for masked hypertension (sensitivity, 0.23-0.38; specificity, 0.92-0.96; κ, 0.27-0.36). Nocturnal home BP was higher than asleep ambulatory BP (systolic MD, 2.6-5.0 mmHg; diastolic MD, 2.2-3.2 mmHg) with moderate agreement (κ, 0.33-0.49). Limitations included different hypertension thresholds and HBPM protocols.

conclusionsThe accuracy of HBPM may not be sufficient to replace ABPM as a single test. However, HBPM may be a practical alternative when ABPM is not available, particularly when clinic and home BPs are concordant. Future work is needed to determine the best approach to HBPM in clinical practice.

Indexed as

Blood Pressure Monitoring, AmbulatoryHypertensionAdolescentChildHumansReproducibility of ResultsSensitivity and Specificityambulatory blood pressure monitoringelevated blood pressurehypertensionmasked hypertensionwhite coat hypertension

Identifiers

PMID40334740
PMCPMC13488463

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.