Evidence map›Paper›PMID 40337339›Full record

ArticleERJ open research2025

A systematic review investigating the impact of dual use of e-cigarettes and conventional cigarettes on smoking cessation.

Josef Hamoud, Reiner Hanewinkel, Stefan Andreas, Omar Ammous, Marc Saalfrank, Steve Sussman, Jennifer B Unger, Charlotta Pisinger, Tim Mathes

Abstract read
In one paragraph

Article in ERJ open research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Josef HamoudDepartment of Medical Statistics, University Medical Center Göttingen, Georg-August University Göttingen, Göttingen, Germany.
Reiner HanewinkelInstitut für Therapie- und Gesundheitsforschung, IFT-Nord gGmbH, Kiel, Germany.
Stefan AndreasLungenfachklinik Immenhausen und Universitätsmedizin Göttingen, Kardiologie und Pneumologie, Deutsches Zentrum Lungenforschung, Göttingen, Germany.ORCID https://orcid.org/0000-0003-3918-6909
Omar AmmousDepartment of Medical Statistics, University Medical Center Göttingen, Georg-August University Göttingen, Göttingen, Germany.ORCID https://orcid.org/0000-0003-1671-1432
Marc SaalfrankDepartment of Medical Statistics, University Medical Center Göttingen, Georg-August University Göttingen, Göttingen, Germany.
Steve SussmanDepartment of Population and Public Health Sciences, University of Southern California, Los Angeles, CA, USA.
Jennifer B UngerDepartment of Population and Public Health Sciences, University of Southern California, Los Angeles, CA, USA.ORCID https://orcid.org/0000-0001-9064-6603
Charlotta PisingerCenter for Clinical Research and Prevention, Bispebjerg-Frederiksberg University Hospital, Capital Region of Denmark, Copenhagen, Denmark.
Tim MathesDepartment of Medical Statistics, University Medical Center Göttingen, Georg-August University Göttingen, Göttingen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Dual use (DU) of conventional cigarettes (CC) and e-cigarettes (EC) has emerged as a common pattern among youth and adult populations. This review aims to investigate whether DU can promote smoking cessation. Methods: A systematic search was conducted in accordance with PRISMA guidelines, and all longitudinal studies reporting transitions between DU, exclusive EC use and exclusive CC use were included. Two independent reviewers screened and read all records. Use status transitions among DU were compared to transitions among exclusive e-cigarette users and exclusive CC smokers. Results: 46 records (16 original studies) were identified. Of 16 included studies, eight could be pooled for meta-analysis. The studies showed great heterogeneity, and many presented moderate to high risks of bias. Most DU who changed state transitioned to cigarette smoking. Baseline DU were less likely to report a transition into complete abstinence compared to exclusive CC smokers and exclusive EC users. About one-fifth of DU remained in the same use status after >16-24 months, exposing them to DU for a prolonged time. After >24-48 months, 8% of DU maintained DU. Conclusion: Current evidence suggests that DU is not a first step towards smoking cessation, with most DU continuing cigarette consumption either through persistent DU or exclusive CC smoking. Relatively fewer DU transitioned into complete nicotine abstinence compared to exclusive CC and exclusive EC users. The concerns raised about limitations of current evidence highlight the need for more research focused on use status transitions among DU.

Identifiers

PMID40337339
PMCPMC12053992

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.