ArticleFrontiers in public health2025
Anemia as a mediator: bridging the frailty index and hip fractures in older Chinese populations.
Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Association between sleep duration and sarcopenic obesity: The mediating role of hemoglobin level.PloS one · 2026Article
- The impact of ADL disability in middle-aged and older adults on the incidence of hip fractures and the mediating role of depression: a longitudinal evidence from CHARLS.Frontiers in medicine · 2025Article
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Authors and funding
6 authors.
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Abstract
Background: Hip fracture is a significant global public health issue. The link and mechanisms between frailty index (FI) and hip fracture remain unclear. This research examined how anemia mediates the link between FI and hip fracture. Methods: The study analyzed data from the 2015 China Health and Retirement Longitudinal Study (CHARLS), which included 6,326 participants aged 60 and above. The mediating role of anemia in the relationship between FI and hip fracture was examined using bootstrap analysis and linear regression models. Results: After controlling for confounding variables, FI was positively associated with hip fracture (OR = 1.13, 95% CI: 1.09-1.16; Conclusions: The findings suggest that FI and anemia were positively associated with hip fracture, and anemia played a mediating role in the association between FI and hip fracture. Intervention based on exercise, nutrition and medical management can combat anemia and reduce FI and may be an effective way to prevent or delay hip fractures.
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