Evidence map›Paper›PMID 40337758›Full record

ArticleTranslational gastroenterology and hepatology2025

Association between cholecystectomy and chronic kidney disease risk: a nationally retrospective cohort study.

Jiwon Yu, Sangwoo Park, Seogsong Jeong, Sun Jae Park, Jihun Song, Hye Jun Kim, Jaewon Lee, Ahryoung Ko, Si Nae Oh, Sang Min Park

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Article in Translational gastroenterology and hepatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jiwon Yu *Department of Biomedical Sciences, Seoul National University Graduate School, Seoul, South Korea.
Sangwoo Park *Department of Biomedical Sciences, Seoul National University Graduate School, Seoul, South Korea.
Seogsong JeongDepartment of Biomedical Informatics, Korea University College of Medicine, Seoul, South Korea.
Sun Jae ParkDepartment of Biomedical Sciences, Seoul National University Graduate School, Seoul, South Korea.
Jihun SongDepartment of Biomedical Sciences, Seoul National University Graduate School, Seoul, South Korea.
Hye Jun KimDepartment of Biomedical Sciences, Seoul National University Graduate School, Seoul, South Korea.
Jaewon LeeDepartment of Psychiatry, University of Rochester Medical Center, Rochester, New York, USA.
Ahryoung KoDepartment of Family Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, South Korea.
Si Nae OhDepartment of Family Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, South Korea.
Sang Min ParkDepartment of Biomedical Sciences, Seoul National University Graduate School, Seoul, South Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Cholecystectomy, a common surgery, has been associated to various health issues. Some evidence suggests associations between gallbladder removal and elevated risks of metabolic and cardiovascular diseases. However, the potential association between cholecystectomy and chronic kidney disease (CKD) remains understudied. This study aims to investigate the potential relationship between cholecystectomy and CKD risk using a large, population-based cohort. Methods: A retrospective cohort study was conducted using data from the National Health Insurance Service (NHIS) of Korea [2011-2019]. A total of 2,885 participants who underwent cholecystectomy were matched with 8,653 controls. We matched 2,885 cholecystectomy patients with 8,653 controls (1:3 ratio) by sex and propensity score. The incidence of CKD was followed from the surgery date until death or 2019. Results: During a mean follow-up time of 6.04 years, 239 CKD cases were identified. The risk of CKD was significantly increased in the cholecystectomy group compared with the non-cholecystectomy group after adjustment for covariates [adjusted hazard ratio (aHR) 1.89; 95% confidence interval (CI): 1.55-2.31]. This association was observed more than 3 years after cholecystectomy (aHR 1.68; 95% CI: 1.38-2.05) and were consistent across strata of sex, age group, household income, physical activity, and smoking status. Conclusions: Post-cholecystectomy patients might have a higher risk of CKD, and this increased risk could persist over time. Further long-term and in-depth studies are needed to explore the association between cholecystectomy and CKD.

Indexed as

big dataCholecystectomychronic kidney disease (CKD)

Identifiers

PMID40337758
PMCPMC12056102

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.