Evidence map›Paper›PMID 40338046›Full record

ArticleAnnals of behavioral medicine : a publication of the Society of Behavioral Medicine2025

Sexual identity differences in ideal cardiovascular health among cisgender adults in the All of Us Research Program.

Billy A Caceres, Yashika Sharma, Danny Doan, Rohith Ravindranath, Vince Nguyen, Ipek Ensari, Joseph Belloir, Yu Zheng Lim, Stephanie Cook

Abstract read
In one paragraph

Article in Annals of behavioral medicine : a publication of the Society of Behavioral Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Billy A CaceresCenter for Sexual and Gender Minority Health Research, Columbia University School of Nursing, 560 West 168th Street, Room 603, New York, NY 10032, United States.ORCID 0000-0001-6865-5546
Yashika SharmaUniversity of Connecticut School of Nursing, Storrs, CT 06269, United States.ORCID 0000-0002-3178-0885
Danny DoanCenter for Sexual and Gender Minority Health Research, Columbia University School of Nursing, 560 West 168th Street, Room 603, New York, NY 10032, United States.ORCID 0000-0001-8769-994X
Rohith RavindranathDepartment of Ophthalmology, Stanford School of Medicine, Stanford, CA 94305, United States.ORCID 0000-0003-3438-6047
Vince NguyenEmory University Rollins School of Public Health, Atlanta, GA, 30322, United States.
Ipek EnsariHasso Plattner Institute for Digital Health at Icahn School of Medicine at Mount Sinai, New York, NY 10029, United States.ORCID 0000-0001-7745-8501
Joseph BelloirColumbia University School of Nursing, New York, NY 10032, United States.ORCID 0000-0001-9352-9760
Yu Zheng LimCenter for Sexual and Gender Minority Health Research, Columbia University School of Nursing, 560 West 168th Street, Room 603, New York, NY 10032, United States.
Stephanie CookDepartment Biostatistics and Social and Behavioral Sciences, New York University School of Global Public Health, New York, NY, 10003, United States.ORCID 0000-0003-4505-0813

Funding

Technology to Empower Changes in Health (TECH) Network Participant Technologies CenterU24OD023176 · OD · SCRIPPS RESEARCH INSTITUTE, THE · PI TOPOL, ERIC JEFFREY · 2016 to 2022
$204.7M
Precision Medicine Initiative Cohort Program BiobankU24OD023121 · OD · MAYO CLINIC ROCHESTER · PI CEKANOVA, MARIA, CICEK, MINE · 2016 to 2024
$185.5M
Enhancing All of Us Data Resources for Nutrition Precision Health: the All of Us Data and Research CenterU2COD023196 · OD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GLAZER, DAVID, HARRIS, PAUL A. · 2016 to 2022
$143.7M
Adaptive Platform for Personalized EngagementU24OD023163 · OD · VIGNET, INC. · PI JAIN, PRADUMAN · 2017 to 2020
$102.6M
University of Arizona-Banner Health All of Us Research Program OT2OD026549 · OD · UNIVERSITY OF ARIZONA · PI MORENO, FRANCISCO A, REIMAN, ERIC MICHAEL · 2018 to 2023
$78.9M
California Precision Medicine Research Program ConsortiumOT2OD026552 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ANTON-CULVER, HODA A, OHNO-MACHADO, LUCILA · 2018 to 2023
$73.4M
All of Us PennsylvaniaOT2OD026554 · OD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E, VISWESWARAN, SHYAM · 2018 to 2023
$72.1M
New York City Consortium for Precision MedicineOT2OD026556 · OD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BIER, LOUISE E, GHARAVI, ALI G · 2018 to 2023
$67.3M
SouthEast Enrollment Center (SEEC) OT2OD026551 · OD · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI CARRASQUILLO, OLVEEN, COLON, VIVIAN · 2018 to 2023
$62.8M
Southern All of Us NetworkOT2OD026548 · OD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI FOUAD, MONA N., KORF, BRUCE R · 2018 to 2023
$60.5M
Illinois Precision Medicine Consortium OT2OD026557 · OD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI AHSAN, HABIBUL, ARGOS, MARIA · 2018 to 2023
$60.5M
The New England Precision Medicine Consortium of the All of Us Research ProgramOT2OD026553 · OD · MASSACHUSETTS GENERAL HOSPITAL · PI CLARK, CHERYL RENEE, KARLSON, ELIZABETH W · 2018 to 2023
$58.8M
American Heart Association 899585Biobank 1 U24 OD023121Communications and Engagement 3 OT2 OD023205Community Partners 1 OT2 OD025277Data and Research Center 5 U2C OD023196Federally Qualified Health Centers HHSN 263201600085UNCATS NIH HHS TL1 TR001875NCATS NIH HHS TL1TR001875NHLBI NIH HHS K01 HL146965NHLBI NIH HHS K01HL146965NHLBI NIH HHS R01 HL168489NHLBI NIH HHS R56 HL168489NIH HHS OT2 OD023205NIH HHS OT2 OD023206NIH HHS OT2 OD025276NIH HHS OT2 OD025277NIH HHS OT2 OD025315NIH HHS OT2 OD025337NIH HHS OT2 OD026548NIH HHS OT2 OD026549NIH HHS OT2 OD026550NIH HHS OT2 OD026551NIH HHS OT2 OD026552NIH HHS OT2 OD026553NIH HHS OT2 OD026554NIH HHS OT2 OD026555NIH HHS OT2 OD026556NIH HHS OT2 OD026557NIH HHS U24 OD023121NIH HHS U24 OD023163NIH HHS U24 OD023176NIH HHS U2C OD023196NINR NIH HHS T32 NR007969NINR NIH HHS T32NR007969ODCDC CDC HHSODCDC CDC HHS U24 OD023176Participant Technology Systems Center 1 U24 OD023163Regional Medical Centers 1 OT2 OD026549
6 · The paper itself

Abstract

backgroundCardiovascular health (CVH) disparities have been documented among sexual minority adults, yet prior research has focused on individual CVH metrics. We sought to examine sexual identity differences in CVH using the American Heart Association's composite measure of ideal CVH, which provides a more comprehensive assessment of future CVD risk.

methodsData from the All of Us Research Program were analyzed. Sexual identity was categorized as heterosexual, gay/lesbian, bisexual, or other. Individual CVH health metrics and cumulative ideal CVH (range 0-100) were assessed. We ran sex-stratified multiple linear regression models to estimate differences across individual CVH metrics and cumulative ideal CVH between sexual minority and heterosexual adults. We also explored differences in CVH across racial/ethnic and age groups.

resultsThe sample included 11 047 cisgender adults with a mean age of 61.1 years (± 13.85); 80% were non-Hispanic White. Lesbian women, gay men, and bisexual women reported greater nicotine exposure than their heterosexual counterparts. Compared to heterosexual men, gay men (B [95% CI] = -8.95 [-14.50, -3.39]) had worse physical activity scores. Gay men also had better body mass index scores than heterosexual men (B [95% CI] = 3.21 [0.09, 6.33]). Bisexual women and men had lower cumulative ideal CVH scores than heterosexual adults. Exploratory analyses revealed several differences in individual CVH metrics and cumulative ideal CVH across racial/ethnic and age groups.

conclusionsClinical interventions to improve the CVH of bisexual adults are needed. Findings can inform the design of interventions that are tailored for specific subgroups of sexual minority adults.

Indexed as

Cardiovascular DiseasesHealth Status DisparitiesHeterosexualitySexual and Gender MinoritiesAdultAgedFemaleHumansMaleMiddle AgedUnited Statescardiovascular healthepidemiologyhealth equityhealth promotionsexual minority

Identifiers

PMID40338046
PMCPMC12070190

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.