Evidence map›Paper›PMID 40338313›Full record

ArticleApplied microbiology and biotechnology2025

Ethylene glycol metabolism in the oleaginous yeast Rhodotorula toruloides.

Vittorio Giorgio Senatore, Alīna Reķēna, Valeria Mapelli, Petri-Jaan Lahtvee, Paola Branduardi

Abstract read
In one paragraph

Article in Applied microbiology and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Vittorio Giorgio Senatore *Department of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza Della Scienza 2, 20126, Milan, Italy.ORCID http://orcid.org/0000-0001-6826-6209
Alīna Reķēna *Department of Chemistry and Biotechnology, Tallinn University of Technology, Akadeemia Tee 15, Tallinn, Estonia.ORCID http://orcid.org/0000-0001-7597-6954
Valeria MapelliDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza Della Scienza 2, 20126, Milan, Italy.ORCID http://orcid.org/0000-0001-8724-3221
Petri-Jaan LahtveeDepartment of Chemistry and Biotechnology, Tallinn University of Technology, Akadeemia Tee 15, Tallinn, Estonia.ORCID http://orcid.org/0000-0002-3327-3190
Paola BranduardiDepartment of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza Della Scienza 2, 20126, Milan, Italy. paola.branduardi@unimib.it.ORCID http://orcid.org/0000-0003-4115-7015

Funding

Estonian Research Council PRG1101Estonian Research Council RE.4.09.22-0041European COST programme Action Nº CA18229European Union's Horizon 2020 research and innovation programme 101036838Ministero dell'Istruzione e del Merito 2020SBNHLHNextGenerationEU ECS 000037
6 · The paper itself

Abstract

The agro-food chain produces an impressive amount of waste, which includes not only lignocellulosic biomass, but also plastic, used for both protective films and packaging. Thanks to advances in enzymatic hydrolysis, it is now possible to imagine an upcycling that valorizes each waste through microbial fermentation. With this goal in mind, we first explored the ability of the oleaginous red yeast Rhodotorula toruloides to catabolize ethylene glycol (EG), obtained by the hydrolysis of polyethylene terephthalate (PET), in the presence of glucose in batch bioreactor experiments. Secondly, we focused on the physiology of EG catabolism in the presence of xylose as a sole carbon source, and in a mixture of glucose and xylose. Our results show that EG is metabolized to glycolic acid (GA) in all tested conditions. Remarkably, we report for the first time that the consumption of EG improves xylose bioprocess, possibly alleviating a cofactor imbalance by regenerating NAD(P)H. Consumption of EG in the presence of glucose started after the onset of the nitrogen limitation phase, while no significant differences were observed with the control; a 100% mol mol

Indexed as

Ethylene GlycolRhodotorulaBiomassBioreactorsFermentationGlucoseGlycolatesHydrolysisXyloseEthylene GlycolGlucoseGlycolatesglycolic acidXyloseEthylene glycolGlucoseGlycolic acidPolyethylene terephthalateRhodotorula toruloidesXylose

Identifiers

PMID40338313
PMCPMC12062128

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.