Evidence map›Paper›PMID 40338703›Full record

ArticleSubstance use & misuse2025

Intimate Partner Violence Predicts Alcohol and Substance Use Among Young Sexual and Gender Minorities Assigned Male at Birth: A Longitudinal Analysis of the RADAR Cohort.

Nicholas Metheny, Yue Pan, Dalton Scott, Michael E Newcomb, Brian Mustanski

Abstract read
In one paragraph

Article in Substance use & misuse, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nicholas MethenyNell Hodgson Woodruff School of Nursing, Emory University, Atlanta, Georgia, USA.ORCID 0000-0003-2295-2945
Yue PanMiller School of Medicine, University of Miami, Miami, Florida, USA.
Dalton ScottSchool of Nursing and Health Studies, University of Miami, Coral Gables, Florida, USA.ORCID 0000-0003-2312-4463
Michael E NewcombInstitute for Sexual and Gender Minority Health and Wellbeing, Northwestern University, Chicago, Illinois, USA.ORCID 0000-0002-8431-2946
Brian MustanskiInstitute for Sexual and Gender Minority Health and Wellbeing, Northwestern University, Chicago, Illinois, USA.ORCID 0000-0001-9222-5116

Funding

The RADAR cohort study of multilevel Influences on HIV and substance useU01DA036939 · NIDA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Brian Mustanski, Michael E Newcomb · 2014 to 2026
$29.5M
PRIDEnet for the All of Us Research Program OT2OD025276 · OD · STANFORD UNIVERSITY · PI LUNN, MITCHELL RYAN, OBEDIN-MALIVER, JUNO · 2017 to 2024
$13.0M
Substance use and DNA methylation at the intersection of sex and genderR01DA052016 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FLENTJE, ANNESA · 2020 to 2023
$2.9M
Mentoring the next generation of substance use, HIV, and epigenetic researchers in sexual and gender minority healthK24DA057874 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Annesa Flentje · 2023 to 2026
$793k
NIDA NIH HHS K24 DA057874NIDA NIH HHS R01 DA052016NIDA NIH HHS U01 DA036939NIH HHS OT2 OD025276
6 · The paper itself

Abstract

backgroundIntimate partner violence (IPV) is a serious public health issue in sexual and gender minority people assigned male at birth (SGM-AMAB), with rates at or above those of cisgender women. However, there is little research on how IPV exposure may impact alcohol and drug use (DU) in this population, impeding holistic intervention development. This study investigated whether experiences of IPV lead to higher rates of substance use over time among SGM-AMAB.

methodsData from the RADAR cohort study of Chicago-based SGM-AMAB (n=1,239) were used. Cross-lagged generalized estimating equations with repeated measures and Poisson regression models examined if experiences of IPV at one timepoint predicted DU and hazardous alcohol use 6 months later over a five-year period.

findingsAbout one in five (19%) participants reported physical, sexual, or emotional IPV in the six months before visit 1. While all participants' DU increased across the study period (adjusted risk ratio [aRR] = 1.026, 95% CI = 1.012-1.041, p = .0003), participants reporting any IPV at a given timepoint were more likely to report greater DU 6 months later (aRR = 1.145, CI = 1.055-1.242, p = .0012) than those who did not report IPV. Similarly, participants reporting any IPV were more likely to report high-risk alcohol use 6 months later (aRR = 1.033, 95% CI = 1.002-1.064, p = .0344).

conclusionThis study is among the first to investigate temporal relationships between IPV, DU, and hazardous alcohol use in SGM-AMAB. The findings indicate a high burden of IPV, alcohol misuse, and substance misuse in this population, reinforcing that both violence and substance use are important issues in these communities. Results suggest IPV prevention and mitigation should be integrated into holistic substance use reduction efforts for SGM-AMAB. SHORT SUMMARY: This longitudinal study examined how IPV affects substance and alcohol use among SGM-AMAB. Using data from 1,239 participants over five years, the research found that experiencing IPV significantly predicted increased drug use and hazardous alcohol consumption six months post-violence. This study provides critical evidence supporting the integration of IPV prevention and mitigation into substance use interventions for SGM-AMAB communities.

Indexed as

Alcohol DrinkingIntimate Partner ViolenceSexual and Gender MinoritiesSubstance-Related DisordersAdolescentAdultChicagoFemaleHumansLongitudinal StudiesMaleYoung Adultalcohol usedrug useintimate partner violencelongitudinal datasexual and gender minorities

Identifiers

PMID40338703
PMCPMC12213151

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.