Evidence mapPaperPMID 40340702Full record

ReviewTissue barriers2025

Tissue microRNA dynamics in sinonasal inverted papilloma: implications for pathology and therapy.

Giovanna Lucia Piazzetta, Nadia Lobello, Corrado Pelaia, Mariaimmacolata Preianò, Nicola Lombardo, Emanuela Chiarella

Abstract readReview
In one paragraph

Review in Tissue barriers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Giovanna Lucia PiazzettaDepartment of Medical and Surgical Sciences, University Magna Graecia of Catanzaro, Catanzaro, Italy.
Nadia LobelloDepartment of Medical and Surgical Sciences, University Magna Graecia of Catanzaro, Catanzaro, Italy.
Corrado PelaiaDepartment of Medical and Surgical Sciences, University Magna Graecia of Catanzaro, Catanzaro, Italy.
Mariaimmacolata PreianòDepartment of Medical and Surgical Sciences, University Magna Graecia of Catanzaro, Catanzaro, Italy.
Nicola LombardoDepartment of Medical and Surgical Sciences, University Magna Graecia of Catanzaro, Catanzaro, Italy.
Emanuela ChiarellaDepartment of Medical and Surgical Sciences, University Magna Graecia of Catanzaro, Catanzaro, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sinonasal inverted papilloma (SNIP) is a benign epithelial neoplasm of the Schneiderian membrane, known for its locally aggressive behavior, high recurrence rates, and potential for malignant transformation into sinonasal squamous cell carcinoma (SNSCC). Emerging evidence emphasizes the role of microRNAs (miRNAs) in the pathogenesis, progression, and clinical management of SNIP. These small non-coding RNAs regulate key cellular pathways, particularly the PTEN/PI3K/AKT axis, which governs tumor growth, apoptosis resistance, and chemoresistance. Among the miRNAs studied,

Indexed as

MicroRNAsPapilloma, InvertedHumansMicroRNAsHistopathological features of SNIPmicroRNA-targeted therapy in SNIPmolecular biomarkers in SNIPsinonasal inverted papilloma (SNIP)tumorigenesis in sinonasal inverted papilloma

Identifiers

PMID40340702
PMCPMC12667619

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.