Evidence map›Paper›PMID 40340722›Full record

ArticleBMC psychiatry2025

The association of chronotype on depression in adolescents: the mediating role of sensation seeking and sleep quality.

Fangyi Wang, Ying Zhou, Xiao Hou, Shifen Ni, Xiaodi Xia, Tanwei Zhang, Yunyan Zhang, Xiangyu Li, Keyi Wen, Yutong Wang and 2 more

Abstract read
In one paragraph

Article in BMC psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Fangyi Wang *Department of Psychiatry, Key Laboratory of Major Brain Disease and Aging Research (Ministry of Education), The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Ying Zhou *Department of Psychiatry, Key Laboratory of Major Brain Disease and Aging Research (Ministry of Education), The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Xiao HouDepartment of Clinical Medicine, Chongqing Medical and Pharmaceutical College, Chongqing, China.
Shifen NiDepartment of Psychiatry, Key Laboratory of Major Brain Disease and Aging Research (Ministry of Education), The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Xiaodi XiaDepartment of Psychiatry, Key Laboratory of Major Brain Disease and Aging Research (Ministry of Education), The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Tanwei ZhangDepartment of Psychiatry, Key Laboratory of Major Brain Disease and Aging Research (Ministry of Education), The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Yunyan ZhangDepartment of Psychiatry, Key Laboratory of Major Brain Disease and Aging Research (Ministry of Education), The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Xiangyu LiDepartment of Psychiatry, Key Laboratory of Major Brain Disease and Aging Research (Ministry of Education), The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Keyi WenDepartment of Psychiatry, Key Laboratory of Major Brain Disease and Aging Research (Ministry of Education), The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Yutong WangSchool of Nursing, Chongqing Medical University, Chongqing, China.
Wenfen ZhuSchool of Nursing, Chongqing Medical University, Chongqing, China. 1156947778@qq.com.
Yixiao FuDepartment of Psychiatry, Key Laboratory of Major Brain Disease and Aging Research (Ministry of Education), The First Affiliated Hospital of Chongqing Medical University, Chongqing, China. fuyixiaoresearch@126.com.

Funding

Chongqing Municipal Education Commission KJZD-K202300501Chongqing Postgraduate Education Teaching Reform Research Project YJG233058Intelligent Medicine Research Project of Chongqing Medical University ZHYX202218Natural Science Foundation Chongqing, China CSTB2022NSCQ-MSX0121Program for Youth Innovation in Future Medicine of Chongqing Medical University W0107
6 · The paper itself

Abstract

objectivesThis study explores the relationships among chronotype, sensation seeking, sleep quality and depressive symptoms in adolescents with diagnosed depression, aiming to clarify the mechanisms by which chronotype is associated with depression.

methodsThis cross-sectional study assessed 216 adolescents with diagnosed depression using a demographic questionnaire, the Morningness-Eveningness Questionnaire, the Sensation Seeking Scale, the Pittsburgh Sleep Quality Index, and the Beck Depression Inventory. Descriptive and correlational analyses were performed using SPSS 27.0, and structural equation modeling was conducted via AMOS to explore the mediating roles of sensation seeking and sleep quality in the relationship between chronotype and depression.

resultsThe study found that 60.6% of adolescents with depression were evening chronotypes. Evening chronotype was associated with higher sensation seeking (r = -0.134, p < 0.05), poorer sleep quality (r = -0.303, p < 0.01), and more severe depressive symptoms (r = -0.376, p < 0.01). Chronotype showed a direct effect on depressive symptoms (effect size = -0.318, 95% CI = -0.602 to -0.049, p < 0.05) and an indirect effect via sleep quality, accounting for 80.5% of the total effect. While sensation seeking alone was not a significant mediator, it contributed to a chain mediation with sleep quality, accounting for 13% of the total effect (combined effect size = -0.053, 95% CI = -0.163 to -0.005, p < 0.01).

conclusionsChronotype may play a significant role in adolescent depression, with both direct and indirect effects mediated by sleep quality and sensation seeking. The findings highlight the potential importance of sleep quality as a mediating factor, indicating that interventions targeting sleep improvement could be a promising avenue for further exploration in alleviating depressive symptoms in adolescents.

Indexed as

Adolescent BehaviorCircadian RhythmDepressionSleep QualityAdolescentChronotypeCross-Sectional StudiesFemaleHumansMaleSleepSurveys and QuestionnairesAdolescentChronotypeDepressionSensation seekingSleep quality

Identifiers

PMID40340722
PMCPMC12060567

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.