Evidence map›Paper›PMID 40340729›Full record

ArticleJournal of Alzheimer's disease : JAD2025

Evaluation of early-phase

Jose Antonio Lojo-Ramírez, Paula Fernández-Rodríguez, Miriam Guerra-Gómez, Alba Marta Marín-Cabañas, Emilio Franco-Macías, Jose Manuel Jiménez-Hoyuela-García, David García-Solís

Abstract readComparative Study
In one paragraph

Article in Journal of Alzheimer's disease : JAD, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Italian intersocietal recommendations for restructuring the diagnostic-therapeutic pathway for the implementation and appropriate use of anti-amyloid monoclonal antibodies in Alzheimer's disease.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jose Antonio Lojo-RamírezInstituto de Biomedicina de Sevilla, IBiS/Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, España.ORCID 0000-0003-4945-8250
Paula Fernández-RodríguezInstituto de Biomedicina de Sevilla, IBiS/Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, España.
Miriam Guerra-GómezInstituto de Biomedicina de Sevilla, IBiS/Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, España.
Alba Marta Marín-CabañasUnidad de Memoria, Servicio de Neurología, Hospital Universitario Virgen del Rocío, Sevilla, España.
Emilio Franco-MacíasUnidad de Memoria, Servicio de Neurología, Hospital Universitario Virgen del Rocío, Sevilla, España.ORCID 0000-0003-4186-1037
Jose Manuel Jiménez-Hoyuela-GarcíaInstituto de Biomedicina de Sevilla, IBiS/Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, España.
David García-SolísInstituto de Biomedicina de Sevilla, IBiS/Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, España.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundImaging biomarkers are essential in Alzheimer's disease (AD) diagnosis, particularly since the introduction of the ATN criteria by the NIA-AA. These criteria include amyloid-β plaques (amyloid PET), fibrillar tau (tau PET), and neurodegeneration (FDG PET or MRI). Early-phase amyloid PET imaging has shown a strong correlation with FDG PET at the group level.ObjectiveThis study evaluates the comparability of early-phase FBB PET (eFBB) perfusion imaging and FDG PET metabolic imaging at both group and individual levels.MethodsA retrospective study included 103 patients with mild cognitive impairment (MCI) or mild dementia suspected of AD who underwent FDG PET and dual-phase

Indexed as

Alzheimer DiseaseAniline CompoundsCognitive DysfunctionFluorodeoxyglucose F18Positron-Emission TomographyStilbenesAgedAged, 80 and overBiomarkersBrainFemaleHumansMaleMiddle AgedRadiopharmaceuticalsRetrospective Studies4-(N-methylamino)-4'-(2-(2-(2-fluoroethoxy)ethoxy)ethoxy)stilbeneAniline CompoundsBiomarkersFluorodeoxyglucose F18RadiopharmaceuticalsStilbenesAlzheimer's diseaseamyloid PETbrain perfusiondementiaFlorbetabenneuroimaging

Identifiers

PMID40340729
PMCPMC12231879

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.