Evidence map›Paper›PMID 40342998›Full record

ArticleFrontiers in pharmacology2025

Druggable proteins of

Saman Sohail, Ayesha Wisal, Sobia Rana, Rao Muhammad Abid Khan, Asad Ullah, Farooq-Ahmad Khan, Muhammad Irfan, Muhammad Imran, Paulo V S D Carvalho, Renato Rozental and 2 more

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Comparative Evaluation of Different Fruit Parts ofFoods (Basel, Switzerland) · 2026
    Article
  2. Article
  3. The role of theFrontiers in microbiology · 2026
    Review
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Saman Sohail *Department of Chemistry, Islamia College Peshawar, Peshawar, Pakistan.
Ayesha Wisal *Department of Chemistry, Islamia College Peshawar, Peshawar, Pakistan.
Sobia Rana *Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences (PCMD-ICCBS), University of Karachi, Karachi, Pakistan.
Rao Muhammad Abid Khan *Department of Clinical Microbiology, Sindh Institute of Urology and Transplantation (SIUT), Karachi, Pakistan.
Asad Ullah *Department of Chemistry, Islamia College Peshawar, Peshawar, Pakistan.
Farooq-Ahmad Khan *TWC, HEJ-ICCBS, University of Karachi, Karachi, Pakistan.
Muhammad Irfan *Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences (PCMD-ICCBS), University of Karachi, Karachi, Pakistan.
Muhammad ImranResearch Center for Advanced Materials Science (RCAMS), Department of Chemistry, Faculty of Science, King Khalid University, Abha Aseer, Saudi Arabia.
Paulo V S D CarvalhoCentre for Technological Development in Health (CDTS), Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, Brazil.
Renato RozentalCentre for Technological Development in Health (CDTS), Oswaldo Cruz Foundation (Fiocruz), Rio de Janeiro, Brazil.
Farzana ShaheenDr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences (PCMD-ICCBS), University of Karachi, Karachi, Pakistan.
Syed Shah Hassan *Department of Chemistry, Islamia College Peshawar, Peshawar, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The genus Methods: To explore potential therapeutic targets and inhibitors, we filtered the core genome of Results and Discussion: A set of 39 potential proteins was drastically reduced to only two targets after sequential data mining. The 3D structures of the selected targets (

Indexed as

Alistipes generadruggable targetspharmacokineticssubtractive genomicsTCM/ZINC inhibitorsthermodynamics evaluation

Identifiers

PMID40342998
PMCPMC12058783

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.