Evidence map›Paper›PMID 40346305›Full record

ArticlePlant cell reports2025

A method for maintaining the release of co-suppression and maximally restoring the RDR6 expression.

Na Li, Hailan Wang, Jiayin Wen, Xiangling Liu, Meng Zhang

Abstract read
PubMed Publisher
In one paragraph

Article in Plant cell reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Na LiCollege of Agronomy, Northwest A&F University, Yangling, 712100, Shaanxi, China.
Hailan WangCollege of Agronomy, Northwest A&F University, Yangling, 712100, Shaanxi, China.
Jiayin WenCollege of Agronomy, Northwest A&F University, Yangling, 712100, Shaanxi, China.
Xiangling LiuCollege of Agronomy, Northwest A&F University, Yangling, 712100, Shaanxi, China.
Meng ZhangCollege of Agronomy, Northwest A&F University, Yangling, 712100, Shaanxi, China. zhangm@nwsuaf.edu.cn.ORCID http://orcid.org/0000-0002-0738-7899

Funding

National Natural Science Foundation of China 32171837
6 · The paper itself

Abstract

key messageTissue-specific RDR6 compensation rescues Arabidopsis defects while maintaining seed polyunsaturated fatty acid accumulation, balancing co-suppression relief and key trait retention for modular engineering. The transgene-induced co-suppression of fatty acid desaturase 2 (FAD2) can be effectively released in rdr6 mutant, enabling a significant increase in polyunsaturated fatty acid (PUFA) content in seeds. However, the global suppression of RNA-dependent RNA polymerase 6 (RDR6) compromises plant growth and disease resistance. To address this limitation, we developed a spatiotemporal compensation strategy by restoring RDR6 expression in non-seed tissues using tissue-specific promoters while maintaining its low expression during seed maturation. To implement this goal, we identified P

Indexed as

ArabidopsisArabidopsis ProteinsRNA-Dependent RNA PolymeraseBrassica napusFatty Acid DesaturasesFatty Acids, UnsaturatedGene Expression Regulation, PlantMutationPhenotypePlants, Genetically ModifiedPromoter Regions, GeneticSeedsArabidopsis ProteinsFatty Acid DesaturasesFatty Acids, UnsaturatedRNA-Dependent RNA PolymeraseArabidopsisFAD2PUFARDR6Tissue-specific promoterTransgene co-suppression

Identifiers

PMID40346305

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.