Evidence map›Paper›PMID 40346328›Full record

ReviewJournal of muscle research and cell motility2025

Insights into human muscle biology from human primary skeletal muscle cell culture.

Thomas Francis, Casper Soendenbroe, Norman R Lazarus, Abigail L Mackey, Stephen D R Harridge

Abstract readReview
In one paragraph

Review in Journal of muscle research and cell motility, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Muscle fibre denervation in ageing.Clinical science (London, England : 1979) · 2026
    Review
  2. Article
  3. Review
  4. Biohybrid Tendons Enhance the Power-to-Weight Ratio and Modularity of Muscle-Powered Robots.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  5. Article
  6. Article
  7. Zinc deficiency contributes to blunted myogenesis in chronic kidney disease.American journal of physiology. Cell physiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Thomas FrancisCentre for Human & Applied Physiological Sciences, Basic & Medical Biosciences, Faculty of Life Science & Medicine, King's College London, London, UK. thomas.francis@kcl.ac.uk.ORCID 0000-0002-1021-8834
Casper SoendenbroeInstitute of Sports Medicine Copenhagen, Department of Orthopaedic Surgery, Copenhagen University Hospital-Bispebjerg and Frederiksberg, Copenhagen, Denmark.ORCID 0000-0002-6579-5700
Norman R LazarusCentre for Human & Applied Physiological Sciences, Basic & Medical Biosciences, Faculty of Life Science & Medicine, King's College London, London, UK.ORCID 0000-0002-3519-5034
Abigail L MackeyInstitute of Sports Medicine Copenhagen, Department of Orthopaedic Surgery, Copenhagen University Hospital-Bispebjerg and Frederiksberg, Copenhagen, Denmark.ORCID 0000-0002-2017-4580
Stephen D R HarridgeCentre for Human & Applied Physiological Sciences, Basic & Medical Biosciences, Faculty of Life Science & Medicine, King's College London, London, UK.ORCID 0000-0002-8203-0769

Funding

Lundbeck Foundation R344-2020-254Lundbeck Foundation R402-2022-1387
6 · The paper itself

Abstract

This review arises from the symposium held in honour of Prof Jenny Morgan at UCL in 2024 and the authors would like to acknowledge the outstanding contribution that Prof Morgan has made to the field of translational muscle cell biology. Prof Morgan published a review article in 2010 entitled: Are human and mice satellite cells really the same? In which the authors highlighted differences between species which are still pertinent to skeletal muscle cell culture studies today. To our knowledge there are no comprehensive reviews which outline the considerable work that has been undertaken using human primary skeletal muscle origin cells as the main model system. This review highlights the multitude of muscle biology that has been investigated using human primary cells, as well as discussing the advantages and disadvantages over other cell models. We also discuss future directions for primary cell culture models utilising the latest technologies in cell type specificity and culture systems.

Indexed as

Muscle, SkeletalPrimary Cell CultureSatellite Cells, Skeletal MuscleAnimalsCells, CulturedHumansCell cultureFibroblastsHumanMyoblastsSatellite cellsSkeletal muscle

Identifiers

PMID40346328
PMCPMC12717197

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.