Evidence map›Paper›PMID 40346348›Full record

ArticleCell biochemistry and biophysics2025

Glycyrrhiza pallidiflora Polysaccharide Ameliorates DSS-Induced Colitis by Protecting Intestinal Barrier Integrity.

Dandan Zeng, Weijie Ren, Bo Zhao, Yuanyuan Li, Jinlong Jiao, Tianlu Mo

Abstract read
PubMed Publisher
In one paragraph

Article in Cell biochemistry and biophysics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dandan ZengSchool of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China.
Weijie RenSchool of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China.
Bo ZhaoSchool of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China.
Yuanyuan LiSchool of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China.
Jinlong JiaoSchool of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China.
Tianlu MoSchool of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai, China. motianlu@usst.edu.cn.

Funding

The National Key Research and Development Program of China 2023YFF1103600
6 · The paper itself

Abstract

Ulcerative colitis (UC) is an idiopathic inflammatory bowel disease. Glycyrrhiza pallidiflora polysaccharide (GPP) is an important constituent of a species of Glycyrrhiza pallidiflora, but its therapeutic mechanism in UC mice is not clear. A dextran sulphate sodium salt (DSS)-induced mouse model of UC was established, and GPP was extracted by ultrasound-assisted extraction, optimised to a GPP content of 25.66% by one-factor optimisation. The effects of different doses (100, 200, 300 mg/kg) of GPP on UC were investigated. The results showed that GPP could delay the trend of weight loss, reduce the DAI score and decrease colon damage in mice, and GPP had a better ameliorative effect on enteritis, which provided a theoretical basis for studying the effect of natural products on UC.

Indexed as

ColitisColitis, UlcerativeGlycyrrhizaIntestinal MucosaPolysaccharidesAnimalsColonDextran SulfateDisease Models, AnimalMaleMiceDextran SulfatePolysaccharidesGlycyrrhiza pallidiflora PolysaccharideGut microbiotaUlcerative colitis

Identifiers

PMID40346348

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.