Evidence map›Paper›PMID 40346601›Full record

ArticleInternational journal of retina and vitreous2025

Macular thickness and vascular density assessment using optical coherence tomography and optical coherence tomography angiography imaging in iron ore mine personnel.

Navid Faraji, Seyyed Pouria Tafti, Niloofar Khoshroo, Alireza Khoshrou, Elham Bakhtiari, Saeid Eslami, Nasser Shoeibi, Mohammad Reza Ansari Astaneh, Seyedeh Maryam Hosseini, Majid Abrishami and 3 more

Abstract read
In one paragraph

Article in International journal of retina and vitreous, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Navid FarajiEye Research Center, Mashhad University of Medical Sciences Khatam-al-Anbia Hospital, Razavi Khorasan Province, Qarani Blvd, Mashhad, 9195965919, Iran.
Seyyed Pouria TaftiEye Research Center, Mashhad University of Medical Sciences Khatam-al-Anbia Hospital, Razavi Khorasan Province, Qarani Blvd, Mashhad, 9195965919, Iran.
Niloofar KhoshrooEye Research Center, Mashhad University of Medical Sciences Khatam-al-Anbia Hospital, Razavi Khorasan Province, Qarani Blvd, Mashhad, 9195965919, Iran.
Alireza KhoshrouEye Research Center, Mashhad University of Medical Sciences Khatam-al-Anbia Hospital, Razavi Khorasan Province, Qarani Blvd, Mashhad, 9195965919, Iran.
Elham BakhtiariEye Research Center, Mashhad University of Medical Sciences Khatam-al-Anbia Hospital, Razavi Khorasan Province, Qarani Blvd, Mashhad, 9195965919, Iran.
Saeid EslamiDepartment Of Medical Informatics, Mashhad University Of Medical Sciences, Razavi Khorasan Province, Mashhad, Iran.
Nasser ShoeibiEye Research Center, Mashhad University of Medical Sciences Khatam-al-Anbia Hospital, Razavi Khorasan Province, Qarani Blvd, Mashhad, 9195965919, Iran.
Mohammad Reza Ansari AstanehEye Research Center, Mashhad University of Medical Sciences Khatam-al-Anbia Hospital, Razavi Khorasan Province, Qarani Blvd, Mashhad, 9195965919, Iran.
Seyedeh Maryam HosseiniEye Research Center, Mashhad University of Medical Sciences Khatam-al-Anbia Hospital, Razavi Khorasan Province, Qarani Blvd, Mashhad, 9195965919, Iran.
Majid AbrishamiEye Research Center, Mashhad University of Medical Sciences Khatam-al-Anbia Hospital, Razavi Khorasan Province, Qarani Blvd, Mashhad, 9195965919, Iran.
Hamid Reza HeidarzadehEye Research Center, Mashhad University of Medical Sciences Khatam-al-Anbia Hospital, Razavi Khorasan Province, Qarani Blvd, Mashhad, 9195965919, Iran.
Parnian ArjmandDepartment of ophthalmology, Mississauga Retina Institute, Mississauga, ON, Canada.
Mojtaba AbrishamiEye Research Center, Mashhad University of Medical Sciences Khatam-al-Anbia Hospital, Razavi Khorasan Province, Qarani Blvd, Mashhad, 9195965919, Iran. mojtaba_abrishami@yahoo.com.

Funding

Mashhad University of Medical Sciences 4001520
6 · The paper itself

Abstract

backgroundTo assess macular anatomical and vascular parameters in individuals working in iron ore mines using Optical Coherence Tomography (OCT) and Optical Coherence Tomography Angiography (OCTA) imaging to explore potential correlations between this occupational exposure and retinal changes.

methodsIndividuals from the Sangan iron ore mine in Iran were included in a comparative cross-sectional observational study. An age-matched normal control group was selected from healthy participants employed at Mashhad University of Medical Sciences. Following thorough medical evaluations, participants underwent OCT and OCTA imaging. The macular thickness profile, vessel density (VD) of the superficial (SCP) and deep retinal capillary plexus (DCP), and the area of the foveal avascular zone (FAZ) were measured in our cases and compared with age-matched normal controls.

resultsOne hundred and one individuals, with an average age of 38.3 ± 5.59 years in the case group and 38.5 ± 5.59 years in the control group, were enrolled in the study. The difference in mean foveal thickness between cases (50.75 ± 9.13) and normal controls (50.38 ± 8.29) was not statistically significant (p = 0.758). Similarly, the mean VD in SCP and DCP for the case group (49.08 ± 2.20 and 49.32 ± 2.42, respectively) and the control group (49.45 ± 3.54 and 49.36 ± 3.97) did not show significant differences. Additionally, there were no significant changes (p-value > 0.05) in macular thickness and VD in other retinal regions when comparing the case and control groups.

conclusionThe research did not establish a significant association between occupational exposure in an iron ore mine and retinal structural changes or alterations in macular VD.

Indexed as

Iron ore mine personnelMaculaOptical coherence tomography angiography (OCTA)Optical coherence tomography (OCT)

Identifiers

PMID40346601
PMCPMC12063320

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.