Evidence map›Paper›PMID 40346775›Full record

ArticleEuropean journal of immunology2025

VSIG4-Expressing Macrophages Contribute to Antiparasitic and Antimetastatic Responses in the Peritoneal Cavity.

Els Lebegge, Daliya Kancheva, Jolien Van Craenenbroeck, Sam Ernst, Pauline M R Bardet, Aarushi A Caro, Máté Kiss, Neema Ahishakiye Jumapili, Romina Mora Barthelmess, Maida Zivalj and 16 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in European journal of immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Els LebeggeLaboratory of Cellular and Molecular Immunology, Brussels Center for Immunology (BCIM), Vrije Universiteit Brussel, Brussels, Belgium.
Daliya KanchevaLaboratory of Cellular and Molecular Immunology, Brussels Center for Immunology (BCIM), Vrije Universiteit Brussel, Brussels, Belgium.
Jolien Van CraenenbroeckLaboratory of Cellular and Molecular Immunology, Brussels Center for Immunology (BCIM), Vrije Universiteit Brussel, Brussels, Belgium.
Sam ErnstDepartment of GI Surgery, Ghent University Hospital, Ghent, Belgium.
Pauline M R BardetLaboratory of Cellular and Molecular Immunology, Brussels Center for Immunology (BCIM), Vrije Universiteit Brussel, Brussels, Belgium.ORCID 0000-0003-4454-9823
Aarushi A CaroLaboratory of Cellular and Molecular Immunology, Brussels Center for Immunology (BCIM), Vrije Universiteit Brussel, Brussels, Belgium.
Máté KissLaboratory of Cellular and Molecular Immunology, Brussels Center for Immunology (BCIM), Vrije Universiteit Brussel, Brussels, Belgium.
Neema Ahishakiye JumapiliLaboratory of Cellular and Molecular Immunology, Brussels Center for Immunology (BCIM), Vrije Universiteit Brussel, Brussels, Belgium.
Romina Mora BarthelmessLaboratory of Cellular and Molecular Immunology, Brussels Center for Immunology (BCIM), Vrije Universiteit Brussel, Brussels, Belgium.
Maida ZivaljLaboratory of Cellular and Molecular Immunology, Brussels Center for Immunology (BCIM), Vrije Universiteit Brussel, Brussels, Belgium.
Naela AssafLaboratory of Cellular and Molecular Immunology, Brussels Center for Immunology (BCIM), Vrije Universiteit Brussel, Brussels, Belgium.
Leen AliLaboratory of Myeloid Cell Immunology, VIB Center for Inflammation Research, Brussels, Belgium.ORCID 0000-0002-6782-2338
Yvon ElkrimLaboratory of Cellular and Molecular Immunology, Brussels Center for Immunology (BCIM), Vrije Universiteit Brussel, Brussels, Belgium.
Jesse DemuytereDepartment of GI Surgery, Ghent University Hospital, Ghent, Belgium.
Jan De JongeLaboratory of Molecular Imaging and Therapy (MITH), Vrije Universiteit Brussel, Brussels, Belgium.
Geert RaesLaboratory of Cellular and Molecular Immunology, Brussels Center for Immunology (BCIM), Vrije Universiteit Brussel, Brussels, Belgium.
Eva HadadiLaboratory of Cellular and Molecular Immunology, Brussels Center for Immunology (BCIM), Vrije Universiteit Brussel, Brussels, Belgium.
Nick DevoogdtLaboratory of Molecular Imaging and Therapy (MITH), Vrije Universiteit Brussel, Brussels, Belgium.ORCID 0000-0001-9220-4833
Cécile VinckeLaboratory of Cellular and Molecular Immunology, Brussels Center for Immunology (BCIM), Vrije Universiteit Brussel, Brussels, Belgium.
Kiavash MohavediBrain and Systems Immunology Lab, Brussels Center for Immunology (BCIM), Vrije Universiteit Brussel, Brussels, Belgium.ORCID 0000-0002-0826-4399
Lars VereeckeDepartment of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium.
Wim CeelenDepartment of GI Surgery, Ghent University Hospital, Ghent, Belgium.
Benoit StijlemansLaboratory of Cellular and Molecular Immunology, Brussels Center for Immunology (BCIM), Vrije Universiteit Brussel, Brussels, Belgium.
Damya LaouiLaboratory of Cellular and Molecular Immunology, Brussels Center for Immunology (BCIM), Vrije Universiteit Brussel, Brussels, Belgium.
Sana M ArnoukLaboratory of Cellular and Molecular Immunology, Brussels Center for Immunology (BCIM), Vrije Universiteit Brussel, Brussels, Belgium.
Jo A Van GinderachterLaboratory of Cellular and Molecular Immunology, Brussels Center for Immunology (BCIM), Vrije Universiteit Brussel, Brussels, Belgium.

Funding

Fonds Wetenschappelijk Onderzoek 1154722NFonds Wetenschappelijk Onderzoek 1199323NFonds Wetenschappelijk Onderzoek 1S18523NFonds Wetenschappelijk Onderzoek 1S23316NFonds Wetenschappelijk Onderzoek 1S67421NFonds Wetenschappelijk Onderzoek 1S78122NFonds Wetenschappelijk Onderzoek G090223NFonds Wetenschappelijk Onderzoek S001623N)Kom op tegen KankerStichting tegen KankerVrije Universiteit Brussel.
6 · The paper itself

Abstract

Large peritoneal macrophages (LPMs) play a role as gatekeepers of peritoneal homeostasis by providing a first line of defense against pathogens. A third of the LPMs express the surface receptor VSIG4, but it is unclear whether these cells differ from their VSIG4-negative counterparts and perform dedicated functions. We demonstrate that VSIG4

Indexed as

Colorectal NeoplasmsMacrophages, PeritonealPeritoneal CavityTrypanosoma brucei bruceiAnimalsCell Line, TumorFemaleHumansMaleMiceMice, Inbred C57BLNeoplasm MetastasisPhagocytosisSingle-Domain AntibodiesStaphylococcus aureusSingle-Domain Antibodiescolorectal cancer metastasislarge peritoneal macrophageTrypanosoma brucei brucei infectionVSIG4

Identifiers

PMID40346775
PMCPMC12064866

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.