Evidence map›Paper›PMID 40348777›Full record

ArticleScientific data2025

Time-course liver microarray data from 0 to 14 days in a 70% partial hepatectomy mouse model.

Takashi Nishi, Yoshinao Oki, Reiko Hagiwara, Koichiro Kano

Abstract readDataset
In one paragraph

Article in Scientific data, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Takashi NishiLaboratory of Cell and Tissue Biology, College of Bioresource Sciences, Nihon University, 1866 Kameino, Fujisawa, 252-0880, Japan.ORCID http://orcid.org/0009-0001-1673-4901
Yoshinao OkiLaboratory of Cell and Tissue Biology, College of Bioresource Sciences, Nihon University, 1866 Kameino, Fujisawa, 252-0880, Japan. oki.yoshinao@nihon-u.ac.jp.
Reiko HagiwaraLaboratory of Cell and Tissue Biology, College of Bioresource Sciences, Nihon University, 1866 Kameino, Fujisawa, 252-0880, Japan.
Koichiro KanoLaboratory of Cell and Tissue Biology, College of Bioresource Sciences, Nihon University, 1866 Kameino, Fujisawa, 252-0880, Japan.

Funding

Ministry of Education, Culture, Sports, Science and Technology (MEXT) 19K06444Ministry of Education, Culture, Sports, Science and Technology (MEXT) 24K09289
6 · The paper itself

Abstract

The liver is capable of regeneration, regaining mass through compensatory hypertrophy even after resecting 70% of its mass. However, the underlying regenerative mechanism remains poorly understood. Thus, in this study, microarray data were procured over time, from 0 to 14 days post-70% partial hepatectomy (PH) in mice. This dataset was correlated with the body weight and liver weight measured at the time of liver harvest, allowing us to determine the progress of compensatory hypertrophy in each sample. Furthermore, the impact of individual differences in regenerative capacity was analyzed by preparing three biological replicates at each time point. The microarray data were confirmed to be of high quality based on the RNA integrity number and QC stats of the dataset. The reliability of the dataset was further supported by the results of hierarchical clustering and the expression variation of cell cycle-related genes. This microarray data will contribute to the elucidation of the regenerative mechanism in the 70% PH model.

Indexed as

HepatectomyLiverLiver RegenerationAnimalsMice

Identifiers

PMID40348777
PMCPMC12065778

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.