ArticleScientific reports2025
Association between triglyceride glucose index related parameters and obstructive sleep apnea hypopnea syndrome in a cross sectional study.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Beyond the Apnea-Hypopnea Index: Circulating Biomarkers and Device-Based Metrics for Cardiometabolic Risk Stratification in Obstructive Sleep Apnea.Journal of clinical medicine · 2026Review
- Screening obstructive sleep apnea using clinical questionnaires and the triglyceride-glucose index: a cardiovascular risk-based approach.NPJ primary care respiratory medicine · 2026Article
- Effect of obstructive sleep apnea-hypopnea syndrome on myocardial mechanics in obese patients.Frontiers in cardiovascular medicine · 2026Article
- Triglyceride-glucose index and nocturnal oxygenation impairment in patients with obstructive sleep apnea.Frontiers in endocrinology · 2026Article
- Association of the TyG index and its body fat distribution composites with CHD and MACE risk in adults with OSAHS: incremental discrimination and exploratory mediation analysis.Frontiers in endocrinology · 2026Observational
- Pericoronary Fat Attenuation Index Mediates the Link Between TyG Index and OSA Risk in Type 2 Diabetes.Diabetes, metabolic syndrome and obesity : targets and therapy · 2026Article
- Multidimensional neuropsychological heterogeneity in obstructive sleep apnea: deep clinical phenotyping in a single-center cohort, population proteomic context, and depressive-burden risk stratification.Frontiers in immunology · 2026Article
- Glucose-lipid metabolic dysregulation and sleep fragmentation in obstructive sleep apnea: insights from a large-scale cross-sectional study and exploratory hypoxia-related single-nucleus transcriptomic analysis.Frontiers in nutrition · 2026Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
The relationship between the Triglyceride-Glucose (TyG) index and Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) remains unclear. This study aimed to investigate the association between TyG index-related parameters (TyG, TyG-Body Mass Index (BMI), TyG-Waist Circumference (WC)) and OSAHS. Consecutive subjects referred to our sleep center were enrolled in this study and categorized into four groups based on the severity of OSAHS, as determined by the apnea-hypopnea index (AHI). Multivariate regression analysis was performed to identify independent risk factors associated with TyG index-related parameters in OSAHS. The study included 1250 participants, categorized into 114 without OSAHS, 212 with mild OSAHS, 257 with moderate OSAHS, and 667 with severe OSAHS. Significant differences were observed in fasting glucose levels, TyG, TyG-BMI, and TyG-WC across increasing severity of OSAHS. Multivariate regression showed that TyG-BMI and TyG-WC were independently associated with oxygen desaturation index (ODI), mean oxygen saturation (MSO
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