ArticleNutrition journal2025
The association between total, animal, and plant protein intake and metabolic dysfunction-associated fatty liver disease in overweight and obese children and adolescents.
Article in Nutrition journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.
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Who cites it
8 citing papers in PubMed, 1 synthesis or guideline pooled it.
- High-protein diets and metabolic dysfunction-associated steatotic liver disease: A double-edged sword in liver health.World journal of gastroenterology · 2026Pooled it
- The association between adapted dietary index for gut microbiota and carotid intima-media thickness among overweight or obese children and adolescents.Acta diabetologica · 2026Article
- Dietary Index for Gut Microbiota and the Odds of Metabolic Dysfunction-Associated Fatty Liver Disease in Overweight and Obese Children and Adolescents: A Cross-Sectional Study.Health science reports · 2026Article
- The Evolution of Pediatric MAFLD Research (2014-2023): A Decade-Long Bibliometric Analysis of Emerging TrendsEndocrine, metabolic & immune disorders drug targets · 2026Review
- Ultra-processed food consumption and the risk of developing metabolic dysfunction-associated steatotic liver disease (MASLD): a five-year prospective cohort study in Iranian adults.Journal of health, population, and nutrition · 2025Article
- Dietary antioxidant capacity, flavonoid subclasses, and metabolic dysfunction-associated fatty liver disease in overweight and obese youth.Journal of health, population, and nutrition · 2025Article
- Dietary amino acids and the odds of metabolic dysfunction-associated fatty liver disease (MAFLD) among overweight and obese children and adolescents: a principal component analysis approach.Nutrition & metabolism · 2025Article
- Cultural and Molecular Factors Predisposed to Non-Alcoholic Fatty Liver Disease and Type 2 Diabetes Mellitus.Nutrients · 2025Review
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Authors and funding
7 authors.
Funding
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Abstract
backgroundDietary protein plays a crucial role in the growth and development of children and adolescents. However, recent evidence has shown inconsistent findings regarding the impact of dietary protein sources on health outcomes. This study aimed to investigate the association between total, animal, and plant protein intake and the odds of metabolic dysfunction-associated fatty liver disease (MAFLD) in overweight and obese children and adolescents.
methodsThis cross-sectional study included 505 participants (52.9% males) aged 6-18 years, with a body mass index (BMI)-for-age z-score ≥ 1 based on WHO standards. MAFLD diagnosis followed established consensus definitions. Dietary intake of total, animal, and plant protein was assessed using a validated 147-item food frequency questionnaire. Adjusted logistic regression models were used to estimate odds ratios (ORs) and 95% confidence intervals (CIs) for MAFLD across protein intake and subtype quartiles.
resultsThe participants had a mean age of 10.0 ± 2.3 years and a mean BMI-for-age z-score of 2.70 ± 1.01. Higher animal protein intake was significantly associated with an increased likelihood of MAFLD (highest vs. lowest quartile OR: 2.31; 95% CI: 1.01-5.30). Conversely, higher plant protein intake was significantly associated with reduced odds of MAFLD (highest vs. lowest quartile OR:0.48;95% CI:0.23-0.96). No significant relationship was found between total protein intake and MAFLD odds.
conclusionsOur findings highlight the significance of dietary protein source in the odds of MAFLD among overweight and obese children and adolescents. Further studies are warranted to confirm these findings and explore the underlying mechanisms.
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