Evidence map›Paper›PMID 40350564›Full record

ArticleGut microbes2025

Bacteriophage-driven DNA inversions shape bacterial functionality and long-term co-existence in

Shaqed Carasso, Roni Keshet-David, Jia Zhang, Haitham Hajjo, Dana Kadosh-Kariti, Tal Gefen, Naama Geva-Zatorsky

Abstract read
In one paragraph

Article in Gut microbes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Phase variation inEngineering microbiology · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shaqed CarassoDepartment of Cell Biology and Cancer Science, Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Rappaport Technion Integrated Cancer Center (RTICC), Haifa, Israel.ORCID 0000-0001-5770-9801
Roni Keshet-DavidDepartment of Cell Biology and Cancer Science, Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Rappaport Technion Integrated Cancer Center (RTICC), Haifa, Israel.ORCID 0009-0003-1850-0820
Jia ZhangDepartment of Cell Biology and Cancer Science, Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Rappaport Technion Integrated Cancer Center (RTICC), Haifa, Israel.ORCID 0009-0007-2628-5840
Haitham HajjoDepartment of Cell Biology and Cancer Science, Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Rappaport Technion Integrated Cancer Center (RTICC), Haifa, Israel.ORCID 0000-0002-2395-6078
Dana Kadosh-KaritiDepartment of Cell Biology and Cancer Science, Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Rappaport Technion Integrated Cancer Center (RTICC), Haifa, Israel.ORCID 0000-0003-1897-8616
Tal GefenDepartment of Cell Biology and Cancer Science, Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Rappaport Technion Integrated Cancer Center (RTICC), Haifa, Israel.ORCID 0000-0001-5968-0547
Naama Geva-ZatorskyDepartment of Cell Biology and Cancer Science, Rappaport Faculty of Medicine, Technion - Israel Institute of Technology, Rappaport Technion Integrated Cancer Center (RTICC), Haifa, Israel.ORCID 0000-0002-7303-854X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial genomic DNA inversions, which govern molecular phase-variations, provide the bacteria with functional plasticity and phenotypic diversity. These targeted rearrangements enable bacteria to respond to environmental challenges, such as bacteriophage predation, evading immune detection or gut colonization. This study investigated the short- and long-term effects of the lytic phage Barc2635 on the functional plasticity of

Indexed as

BacteriophagesBacteroides fragilisChromosome InversionDNA, BacterialAnimalsFemaleGastrointestinal MicrobiomeGenome, BacterialGerm-Free LifeMiceMice, Inbred C57BLDNA, BacterialbacteriophagesDNA inversionsfunctional plasticityMicrobiomephase variationpopulation dynamics

Identifiers

PMID40350564
PMCPMC12068327

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.