ArticleFrontiers in medicine2025
Serum uric acid/creatinine ratio and osteoporosis in the elderly: a NHANES study.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Explainable machine learning for osteoporosis detection in patients with osteopenia: model development and validation using routine clinical data from an Asian cohort.Frontiers in endocrinology · 2026Article
- Laboratory biomarkers and radiographic osteolysis after total knee arthroplasty: a retrospective pilot study.Frontiers in surgery · 2026Article
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Authors and funding
5 authors.
Funding
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Abstract
Background: Osteoporosis (OP) is a metabolic bone disorder that is of significant concern to the elderly. However, few studies have investigated the correlation between the serum uric acid to creatinine ratio (UA/Cr) and OP in elderly individuals. This research seeks to examine the connection between UA/Cr levels and OP in older adults. Methods: Data on participant information for the study was obtained from four cycles of the NHANES database. Multivariable logistic regression was employed to examine the correlation between UA/Cr and OP, adjusting for potential confounders such as age, gender, and race. The diagnostic efficacy of UA/Cr for OP was evaluated utilizing ROC curves. Results: Multivariable logistic regression analysis showed that serum UA/Cr levels were significantly lower in individuals with OP than in those without OP. (OR = 0.83 [0.76, 0.91], Conclusion: A higher UA/Cr level within the normal range is associated with a lower risk of OP, providing insights for its diagnosis and risk assessment.
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