Evidence map›Paper›PMID 40351701›Full record

SynthesisReviews in cardiovascular medicine2025

The Risk of New-Onset Atrial Fibrillation in Patients With Conduction System Pacing Versus Right Ventricular Pacing: A Meta-Analysis.

Tingwen Gao, Zhaofeng Li, Wei Li, Xue Wang, Xinxing Xie

Abstract readSystematic Review
In one paragraph

Synthesis in Reviews in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Tingwen GaoDepartment of Cardiology, Rizhao Heart Hospital Qingdao University, 276800 Rizhao, Shandong, China.ORCID https://orcid.org/0009-0002-4601-8671
Zhaofeng LiDepartment of Cardiology, Rizhao Heart Hospital Qingdao University, 276800 Rizhao, Shandong, China.ORCID https://orcid.org/0009-0008-5788-8764
Wei LiDepartment of Cardiology, Rizhao Heart Hospital Qingdao University, 276800 Rizhao, Shandong, China.ORCID https://orcid.org/0009-0003-5075-007X
Xue WangDepartment of Cardiology, Rizhao Heart Hospital Qingdao University, 276800 Rizhao, Shandong, China.ORCID https://orcid.org/0009-0005-3826-7047
Xinxing XieDepartment of Cardiology, Rizhao Heart Hospital Qingdao University, 276800 Rizhao, Shandong, China.ORCID https://orcid.org/0000-0001-5531-8049

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Prior studies have established the safety and efficacy of conduction system pacing (CSP) in improving echocardiographic parameters and clinical outcomes. This meta-analysis aimed to investigate whether CSP could reduce the occurrence of new-onset atrial fibrillation (AF) in comparison to traditional right ventricular pacing (RVP) therapy. Methods: A literature search was performed in PubMed, Embase, and the Cochrane Library to identify relevant clinical studies comparing CSP with RVP from January 2000 to June 2024. The study outcome was new-onset AF after pacemaker implantation. Estimated risk ratios (RR), odds ratio (OR) with 95% confidence intervals (CI) were evaluated. Results: Our analysis included 8 observational studies comprising a total of 2033 patients. The results indicated that 20% (406/2033) of study patients experienced new-onset AF, and CSP was associated with a significantly lower risk of new-onset AF when compared with RVP (RR: 0.44, 95% CI: 0.36-0.54, Conclusion: CSP could reduce the occurrence of new-onset AF compared with RVP, and this benefit appeared to be more pronounced in patients with AVB than those with SND or AVB. However, large scale randomized controlled trials are needed to validate our findings. The PROSPERO Registration: Registration number: CRD42024569052; registration date: July 25, 2024; https://www.crd.york.ac.uk/PROSPERO/view/CRD42024569052.

Indexed as

atrial fibrillationHis bundle pacingleft bundle branch pacingmeta-analysisright ventricular pacing

Identifiers

PMID40351701
PMCPMC12059758

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.