Evidence map›Paper›PMID 40351921›Full record

ArticleCureus2025

Bilateral Optic Disc Edema as the Presenting Sign of Brain Metastasis in Ovarian Carcinoma: A Case Report.

Alka Tripathi, Nivedita Singh, Richa Agarwal, Neha Singh, Amit Thangjam

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alka TripathiOphthalmology, All India Institute of Medical Sciences, Gorakhpur, IND.
Nivedita SinghOphthalmology, All India Institute of Medical Sciences, Gorakhpur, IND.
Richa AgarwalOphthalmology, All India Institute of Medical Sciences, Gorakhpur, IND.
Neha SinghOphthalmology, All India Institute of Medical Sciences, Gorakhpur, IND.
Amit ThangjamOphthalmology, All India Institute of Medical Sciences, Gorakhpur, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brain metastases are one of the common causes of brain tumours in adults and lead to increased morbidity and mortality in cancer patients. Primary cancers such as lung, breast, and melanoma are most likely to metastasize to the brain; however, the incidence of brain metastases in ovarian cancer is low. Papilledema due to brain metastasis occurs when the tumor mass within the brain leads to increased intracranial pressure (ICP). We present an unusual case of bilateral papilledema as the earliest clinical manifestation of brain metastasis in a 48-year-old woman who had undergone treatment for ovarian carcinoma one year ago. We are trying to highlight the rare relapse of ovarian carcinoma (OC) in the form of brain metastasis within one year of therapy and presenting with ophthalmic complaints. Therefore, we emphasize detailed history taking, clinical examination, and neuroimaging of any patient so that early diagnosis and treatment can be done.

Indexed as

best corrected visual acuitybrain tumors (primary or brain metastasis)metastatic ovarian canceroptical coherence tomography (oct)papilledema

Identifiers

PMID40351921
PMCPMC12065931

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.