Evidence map›Paper›PMID 40352071›Full record

ArticleAlpha psychiatry2025

Effectiveness of Eye Movement Desensitization and Reprocessing (EMDR) in Treating Borderline Personality Disorder: A Randomized Controlled Trial.

Marcelo Nvo-Fernandez, Fabiola Salas, Valentina Miño-Reyes, Francisco Ahumada-Méndez, Pablo Medina, Daniela Avello, Síbila Floriano Landim, Marc Via, Nicholas Napolitano, Marcelo Leiva-Bianchi

Abstract read
In one paragraph

Article in Alpha psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Marcelo Nvo-FernandezLaboratory of Methodology for Behavioral Sciences and Neurosciences, Faculty of Psychology, Universidad de Talca, 3460000 Talca, Chile.ORCID https://orcid.org/0000-0002-0183-8708
Fabiola SalasLaboratory of Methodology for Behavioral Sciences and Neurosciences, Faculty of Psychology, Universidad de Talca, 3460000 Talca, Chile.ORCID https://orcid.org/0000-0003-1408-624X
Valentina Miño-ReyesLaboratory of Methodology for Behavioral Sciences and Neurosciences, Faculty of Psychology, Universidad de Talca, 3460000 Talca, Chile.ORCID https://orcid.org/0000-0003-2379-6091
Francisco Ahumada-MéndezLaboratory of Methodology for Behavioral Sciences and Neurosciences, Faculty of Psychology, Universidad de Talca, 3460000 Talca, Chile.ORCID https://orcid.org/0000-0003-3052-2224
Pablo MedinaLaboratory of Methodology for Behavioral Sciences and Neurosciences, Faculty of Psychology, Universidad de Talca, 3460000 Talca, Chile.ORCID https://orcid.org/0009-0006-3708-2435
Daniela AvelloDepartamento de Terapia Ocupacional, Escuela de Ciencias de la Salud, Facultad de Medicina. Pontificia Universidad Católica de Chile, 8940000 Santiago, Chile.ORCID https://orcid.org/0000-0001-8165-3748
Síbila Floriano LandimSchool of Occupational Therapy, Faculty of Psychology, Universidad de Talca, 3465548 Talca, Chile.ORCID https://orcid.org/0000-0002-9292-0853
Marc ViaBrainlab-Grup de Recerca en Neurociència Cognitiva, Departament de Psicologia Clínica i Psicobiologia, Institut de Neurociències, Universitat de Barcelona, 08035 Barcelona, Spain.
Nicholas NapolitanoFaculty of Psychology, Universidad de Talca, 3460000 Talca, Chile.ORCID https://orcid.org/0009-0005-3108-0810
Marcelo Leiva-BianchiLaboratory of Methodology for Behavioral Sciences and Neurosciences, Faculty of Psychology, Universidad de Talca, 3460000 Talca, Chile.ORCID https://orcid.org/0000-0001-6135-9226

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Eye movement desensitization and reprocessing (EMDR) is recommended by major health organizations for trauma treatment, but its efficacy for borderline personality disorder (BPD) remains unestablished. This study aims to evaluate EMDR's effectiveness in treating BPD through a randomized controlled trial (RCT) and compare its outcomes with cognitive behavioral therapy (CBT). Methods: A total of 76 individuals participated in the RCT, with 18 patients (78% female) completing the study. Participants were randomly assigned to receive either EMDR (n = 8) or CBT (n = 10) via teletherapy sessions. Trauma symptoms were assessed using the international trauma questionnaire (ITQ), BPD symptoms were assessed using the Personality Assessment Inventory-Borderline Features Scale (PAI-BOR), and post-traumatic growth (PTG) was assessed using the post-traumatic growth inventory (PTGI). Additionally, attentional evaluations were conducted at behavioral and electroencephalographic levels through an oddball paradigm. A final comparison was made between a participant who did not complete the therapeutic process and a participant who did. Results: Both EMDR and CBT treatments significantly improved trauma and BPD symptoms, as well as post-traumatic growth. The effect size was moderate for ITQ (η Conclusions: Both EMDR and CBT significantly improved trauma and BPD symptoms, as well as post-traumatic growth. Additionally, EMDR showed benefits in response accuracy and speed, with a correct response rate of 97% when comparing two participants (with and without therapy). However, completely clean electroencephalography (EEG) data were not obtained from both participants for a deeper comparison. Clinical Trial Registration: The study was registered at https://doi.org/10.1186/ISRCTN91146045, registration number: ISRCTN91146045, registration date: 21 May 2021.

Indexed as

borderline personality disordercomplex post-traumatic stress disordereye movement desensitization and reprocessingpost-traumatic growthpost-traumatic stress disorderrandomized controlled trial

Identifiers

PMID40352071
PMCPMC12059781

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.