ArticleJournal of diabetes and metabolic disorders2025
Rising type 2 diabetes mellitus-related mortality among young adults in the United States: a nationwide analysis.
Article in Journal of diabetes and metabolic disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Metabolites and proteins may mediate the relationship between diet quality and insulin sensitivity in young adult cohort.Journal of diabetes and metabolic disorders · 2026Article
- Survival and predictors of mortality among adults with type 2 diabetes at a teaching hospital in Ghana: a retrospective cohort study.BMC public health · 2026Article
- Diabetes mellitus in Pakistan: prevalence and preventive management strategies - a comprehensive literature review.Cardiovascular diabetology. Endocrinology reports · 2025Review
Corrections and comments
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Authors and funding
4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Background: Type 2 diabetes mellitus (T2DM) related mortality trends remain understudied among younger adults in the United States (US). This study aims to bridge this gap by using data from a large national database of mortality statistics. Methods: Death certificate data from 1999 to 2020 were extracted from the CDC WONDER database for all the fatalities among US adults aged 25 to 64 years, where T2DM was listed as the underlying or contributing cause of death. Age-adjusted mortality rates (AAMR) per 1 million persons were calculated, and temporal mortality trends were evaluated by computing annual percent change (APC) in AAMRs using the Joinpoint log-linear regression model. Results: A total of 272,155 T2DM-related deaths occurred among US adults aged 25-64 years from 1999 to 2020. The overall AAMR significantly increased from 37.6 in 1999 to 138.36 by 2020 with an APC of 4.8 ( Conclusion: T2DM-related mortality has significantly increased among younger US adults over the last two decades. Higher mortality rates were observed among males, NH American Indians, and residents of rural areas and the Western regions. Graphical Abstract: Type 2 Diabetes Mellitus-related mortality among young adults aged 25-64 years in the United States from 1999 to 2020. Supplementary Information: The online version contains supplementary material available at 10.1007/s40200-025-01626-4.
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