Evidence map›Paper›PMID 40352907›Full record

ArticleFrontiers in neuroscience2025

Voluntary running partially prevents photoreceptor cell death in retinitis pigmentosa.

Stephen K Agadagba, Ying Liang, Kristine N Dalton, Benjamin Thompson, Suk-Yu Yau

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Stephen K AgadagbaCentre for Eye and Vision Research Limited, Hong Kong Science Park, Hong Kong, China.
Ying LiangCentre for Eye and Vision Research Limited, Hong Kong Science Park, Hong Kong, China.
Kristine N DaltonCentre for Eye and Vision Research Limited, Hong Kong Science Park, Hong Kong, China.
Benjamin ThompsonCentre for Eye and Vision Research Limited, Hong Kong Science Park, Hong Kong, China.
Suk-Yu YauCentre for Eye and Vision Research Limited, Hong Kong Science Park, Hong Kong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Retinitis pigmentosa (RP) is a progressive retinal degenerative disorder characterized by photoreceptor cell death, leading to vision loss. Current treatments are limited, and there is a need for non-invasive interventions. This study evaluates the neuroprotective effects of voluntary exercise in an RP mouse model and explores the role of the adiponectin signaling pathway in mediating these effects. Pregnant

Indexed as

adiponectin signalingmitochondrial biogenesisphotoreceptor degenerationretinitis pigmentosavoluntary exercise

Identifiers

PMID40352907
PMCPMC12062024

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.