ArticleJournal of obstetrics and gynaecology of India2025
Evaluation of Dietary Inflammatory Index (DII) and Healthy Eating Index (HEI) in Infertile Women with Polycystic Ovary Syndrome: A Case-Control Study.
Article in Journal of obstetrics and gynaecology of India, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Article
- Association between the diabetes risk reduction diet and polycystic ovary syndrome.BMC nutrition · 2026Article
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Authors and funding
7 authors.
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Abstract
Background: Global infertility affects over 186 million women, posing significant health and societal challenges. Polycystic ovary syndrome (PCOS) is the most prevalent endocrine disorder among reproductive-aged women, often characterized by inflammatory dysregulation. Dietary factors exacerbate insulin resistance and ovulatory dysfunction in PCOS through heightened inflammation. Improving diet quality may mitigate hyperinsulinemia, hyperandrogenism, and inflammation, thereby reducing complications such as infertility. This study examines diet quality using the healthy eating index (HEI) and the dietary inflammatory index (DII) in women with PCOS experiencing infertility. Methods: This case-control study enrolled 80 infertile patients diagnosed with PCOS, alongside 80 healthy individuals without PCOS. Dietary inflammatory Index (DII) and healthy eating index (HEI) scores were computed using a 168-item food frequency questionnaire. Spearman's correlation test was employed to assess variable relationships, and logistic regression was conducted to identify factors influencing PCOS risk. Results: PCOS patients exhibited higher mean DII scores compared to controls (- 2.24 ± 0.80 vs. - 2.57 ± 0.93) and lower HEI scores (55.74 ± 4.89 vs. 58.64 ± 7.16). Adjusted analyses revealed significant inverse relationships between dietary inflammatory and health indices and PCOS risk. Comparison with CRP levels showed significant associations ( Conclusion: This study highlights the significant associations between DII, HEI, and the risk of infertility and PCOS. Improving diet quality may mitigate inflammation and associated PCOS complications, offering potential avenues for intervention and prevention strategies.
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