ArticleAnalytical chemistry2025
Lab-on-a-Scalpel: Medical Tool Incorporating a Disposable Fully 3D-Printed Electrochemical Cell Promoting Drop-Volume Chemical Analysis in the Operating Theater.
Article in Analytical chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- EngineeredMolecules (Basel, Switzerland) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Surgical operations are intricate and invasive procedures that require continuous monitoring of the patient's biochemical profile. Point-of-care testing would allow healthcare professionals to identify abnormalities and make the necessary interventions to minimize the risk of complications and ensure patient safety. To this end, we report the development of a disposable and compact fully 3D-printed electrochemical cell incorporated into a medical scalpel (Lab-on-a-Scalpel), aiming to promote on-site (electro)chemical analysis in the operating theater. This multifunctional device minimizes the number of instruments needed during surgery and can be fabricated on-demand by using a desktop-sized 3D printer at a very low cost. The performance of the Lab-on-a-Scalpel sensing device was evaluated over various electrochemical techniques (cyclic voltammetry, amperometry, and differential pulse voltammetry) and different setups (stirring, drop-volume analysis, polarization potentials, etc.) for the determination of epinephrine. Results showed attractive analytical figures-of-merit, with the limit of detection (LOD) reaching 0.13 μM, and high accuracy in recovery studies conducted on artificial blood samples. Our findings suggest that Lab-on-a-Scalpel is a valuable tool that enables near-patient diagnostics with a minimum sample volume and holds promise to become an essential tool for robotic-assisted surgery.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.