Evidence map›Paper›PMID 40353941›Full record

ReviewNeurochemical research2025

Adrenergic Modulation of Acetylcholine Release at the Mouse Neuromuscular Junctions of Fast-Twitch Skeletal Muscle.

Arsenii Arkhipov, Nikita Zhilyakov, Guzel Sibgatullina, Egor Nevsky, Ellya A Bukharaeva, Alexey M Petrov

Abstract readReview
PubMed Publisher
In one paragraph

Review in Neurochemical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Arsenii ArkhipovLaboratory of Biophysics of Synaptic Processes, Kazan Institute of Biochemistry and Biophysics, FRC Kazan, Scientific Center of RAS, 2/31 Lobachevsky St, Kazan, RT, Russia, 420111.
Nikita ZhilyakovLaboratory of Biophysics of Synaptic Processes, Kazan Institute of Biochemistry and Biophysics, FRC Kazan, Scientific Center of RAS, 2/31 Lobachevsky St, Kazan, RT, Russia, 420111.
Guzel SibgatullinaLaboratory of Biophysics of Synaptic Processes, Kazan Institute of Biochemistry and Biophysics, FRC Kazan, Scientific Center of RAS, 2/31 Lobachevsky St, Kazan, RT, Russia, 420111.
Egor NevskyLaboratory of Biophysics of Synaptic Processes, Kazan Institute of Biochemistry and Biophysics, FRC Kazan, Scientific Center of RAS, 2/31 Lobachevsky St, Kazan, RT, Russia, 420111.
Ellya A BukharaevaLaboratory of Biophysics of Synaptic Processes, Kazan Institute of Biochemistry and Biophysics, FRC Kazan, Scientific Center of RAS, 2/31 Lobachevsky St, Kazan, RT, Russia, 420111. elbukhara@gmail.com.ORCID http://orcid.org/0000-0002-2034-1465
Alexey M PetrovLaboratory of Biophysics of Synaptic Processes, Kazan Institute of Biochemistry and Biophysics, FRC Kazan, Scientific Center of RAS, 2/31 Lobachevsky St, Kazan, RT, Russia, 420111. alexey.petrov@kazangmu.ru.ORCID http://orcid.org/0000-0002-1432-3455

Funding

Russian Science Foundation 23-15-00124
6 · The paper itself

Abstract

The sympathoadrenal system functions as an adaptive and trophic system, ensuring increased vitality in humans and animals. Recent findings suggest that, in addition to its effects on muscle tissue, neuromuscular junctions (NMJs) may represent an important target for action of sympathetic mediators. Here, we presented experimental data on neurotransmitter release modulation by adrenergic ligands at the NMJs of mouse fast-twitch skeletal muscle levator auris longus. Adrenaline (but not noradrenaline) increased both spontaneous and evoked acetylcholine (ACh) release. This effect of adrenaline was accompanied by an increase in action potential-elicited Ca

Indexed as

AcetylcholineMuscle Fibers, Fast-TwitchMuscle, SkeletalNeuromuscular JunctionAnimalsEpinephrineMaleMiceMice, Inbred C57BLNorepinephrineAcetylcholineEpinephrineNorepinephrineAcetylcholineAdrenalineAdrenoreceptorNeuromuscular junctionNeurotransmitter releaseSkeletal muscle

Identifiers

PMID40353941

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.