Trial reportScientific reports2025
Awe reduces depressive symptoms and improves well-being in a randomized-controlled clinical trial.
Trial report in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05676008 (A Study of Positive Emotions With Long COVID), which is not on this map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Study of Positive Emotions With Long COVID (Post-Acute Sequelae of SARS CoV-2 Infection)
Who cites it
4 citing papers in PubMed.
- Alpha and theta audiovisual interventions in a reflective chamber demonstrate acute effects on stress and burnout.NPJ digital medicine · 2026Article
- The neurobiological basis of the awe experience in affective disorders: an exploratory EEG study.Frontiers in systems neuroscience · 2026Article
- "Awe-scillations": EEG spectral and complexity representations of awe.bioRxiv : the preprint server for biology · 2025Article
- Effectiveness of Five-Element Regulatory Therapy for post-COVID syndrome: a retrospective cohort study.Frontiers in medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Emerging evidence suggests that experiences of awe benefit health and well-being. The present investigation examined the efficacy of an awe intervention to improve the psychological health-stress, anxiety, depression, and well-being-of patients living with long COVID. The awe intervention, a Randomized-controlled Clinical Trial, was delivered in synchronous online sessions to patients, across the United States (in April 2023), who met the criteria for long COVID. Results revealed significant improvements in psychological health for those in the awe intervention (N = 30), compared to the control group (N = 38): including decreased stress, decreased depression symptoms, and increased well-being. There were no significant differences between groups in anxiety symptoms. Effect sizes ranged from medium to large (d = 0.78-0.96), demonstrating the robustness of these findings. This work is the first to document that awe can have salutary effects on psychological health, such as reducing symptoms of depression. These findings suggest that a brief awe intervention can improve psychological health in people dealing with chronic stress and physical ailments, as in the case of long COVID.Trial registration. The trial is registered at ClinicalTrials.gov (NCT05676008, 09/01/2023).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.