Evidence map›Paper›PMID 40355653›Full record

Trial reportScientific reports2025

Awe reduces depressive symptoms and improves well-being in a randomized-controlled clinical trial.

María Monroy, Michael Amster, Jake Eagle, Felicia K Zerwas, Dacher Keltner, Javier E López

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05676008 (A Study of Positive Emotions With Long COVID), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05676008 naactive not recruitingnot on this map

A Study of Positive Emotions With Long COVID (Post-Acute Sequelae of SARS CoV-2 Infection)

TypeinterventionalSponsorUniversity of California, DavisRan2023 to 2027Enrolled400ConditionsPost-Acute COVID-19 SyndromeArmsMicrodosing of mindfulness
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. "Awe-scillations": EEG spectral and complexity representations of awe.bioRxiv : the preprint server for biology · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

María MonroyDepartment of Psychology, Yale University, 100 College St, New Haven, CT, 06510, USA. m.monroy@yale.edu.ORCID http://orcid.org/0000-0003-2216-8835
Michael AmsterCollege of Osteopathic Medicine, Touro University California, Vallejo, CA, USA.
Jake EagleLive Conscious, Hawi, HI, USA.
Felicia K ZerwasDepartment of Psychology, New York University, New York, NY, USA.
Dacher KeltnerDepartment of Psychology, University of California, Berkeley, CA, USA.
Javier E LópezCenter for Reducing Health Disparities, University of California, Davis, 2921 Stockton Blvd, Sacramento, CA, 95817, USA. drjlopez@ucdavis.edu.ORCID http://orcid.org/0000-0001-7276-6628

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Emerging evidence suggests that experiences of awe benefit health and well-being. The present investigation examined the efficacy of an awe intervention to improve the psychological health-stress, anxiety, depression, and well-being-of patients living with long COVID. The awe intervention, a Randomized-controlled Clinical Trial, was delivered in synchronous online sessions to patients, across the United States (in April 2023), who met the criteria for long COVID. Results revealed significant improvements in psychological health for those in the awe intervention (N = 30), compared to the control group (N = 38): including decreased stress, decreased depression symptoms, and increased well-being. There were no significant differences between groups in anxiety symptoms. Effect sizes ranged from medium to large (d = 0.78-0.96), demonstrating the robustness of these findings. This work is the first to document that awe can have salutary effects on psychological health, such as reducing symptoms of depression. These findings suggest that a brief awe intervention can improve psychological health in people dealing with chronic stress and physical ailments, as in the case of long COVID.Trial registration. The trial is registered at ClinicalTrials.gov (NCT05676008, 09/01/2023).

Indexed as

COVID-19DepressionStress, PsychologicalAdultAgedAnxietyFemaleHumansMaleMental HealthMiddle AgedQuality of LifeSARS-CoV-2AweDepressionLong COVIDStressWell-being

Identifiers

PMID40355653
PMCPMC12069556

What Socratic holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.