ArticleFrontiers in neurology2025
Multi-regional sequential pain syndrome.
Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
3 citing papers in PubMed.
- Unraveling the Pathophysiological Link Between ALS and SCA: The Role of Ischemic Cerebral Vascular Dissection and the Efficacy of Endovascular Therapy.Cerebellum (London, England) · 2026Article
- Posterior circulation hypoperfusion plays an important role in refractory otalgia: case report.BMC surgery · 2026Article
- Flow diverter implantation for CTA-negative giant vertebral artery dissection aneurysm: a case report.Frontiers in radiology · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: To report a novel clinical entity, "Multi-regional Sequential Pain Syndrome" (MRSPS), and evaluate the relationship between hypoperfusion, cryptogenic vertebral artery dissection (CVAD), and MRSPS. Methods: A 59-year-old female patient, with a chronic MRSPS condition spanning 10-30 years, underwent a comprehensive diagnostic evaluation including cranial CTA, MRI, DSA, and CT perfusion, culminating in the identification of CVAD via dynamic contrast-enhanced computed tomography (DCE-CT). The treatment strategy integrated repairing CVADs with stent implantation to address the hypoperfusion and MRSPS. Results: Following intervention, hypoperfusion achieved complete improvement, and the patient achieved the complete resolution of pain and vertigo, with the modified Rankin Scale (mRS) score of 0 at the 1-year follow-up, signifying full neurological recovery. Conclusion: CVADs, a key cause of brain tissue hypoperfusion in MRSPS, can be effectively treated by repair to alleviate the syndrome.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.