Evidence map›Paper›PMID 40356786›Full record

ArticleFrontiers in pediatrics2025

Ultrasound assessment of hepatomegaly and metabolically-associated fatty liver disease among a sample of children: a pilot project.

Bárbara L Riestra-Candelaria, Wilma Rodríguez-Mojica, Camille Vélez-Morell, Claudia Ramírez-Marcano, Ariana Alvarado-Castillo, Gabriel Camareno-Soto, Loida A González-Rodríguez

Abstract read
In one paragraph

Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bárbara L Riestra-CandelariaDepartment of Anatomy and Cell Biology, School of Medicine, Universidad Central del Caribe, Bayamón, Puerto Rico.
Wilma Rodríguez-MojicaDepartment of Radiological Sciences, School of Medicine, University of Puerto Rico, San Juan, Puerto Rico.
Camille Vélez-MorellMedical Student, School of Medicine, Universidad Central del Caribe, Bayamón, Puerto Rico.
Claudia Ramírez-MarcanoMedical Student, School of Medicine, Universidad Central del Caribe, Bayamón, Puerto Rico.
Ariana Alvarado-CastilloMedical Student, School of Medicine, Universidad Central del Caribe, Bayamón, Puerto Rico.
Gabriel Camareno-SotoMedical Student, School of Medicine, Universidad Central del Caribe, Bayamón, Puerto Rico.
Loida A González-RodríguezDepartment of Medicine-Endocrinology, Diabetes and Metabolism Division, School of Medicine, University of Puerto Rico, San Juan, Puerto Rico.

Funding

Tracking and Evaluation CoreU54GM133807 · NIGMS · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI PORTER, JAMES T. · 2020 to 2024
$17.7M
NIGMS NIH HHS U54 GM133807
6 · The paper itself

Abstract

Introduction: Obesity in children is a global health crisis, with 46% of children in Puerto Rico classified as overweight or obese based on Body Mass Index. This condition is linked to serious comorbidities, including early-onset type 2 diabetes, hypertension, and Metabolic-Associated Fatty Liver Disease (MAFLD), the most common liver disease in U.S. children. This study examines the relationship between body weight, liver size, and texture in children from Puerto Rico. Methods: A craniocaudal right liver lobe (RLL) measurement was performed using a panoramic ultrasound image. RLL length and liver texture were assessed based on fat infiltration. BMI was calculated to classify participants into healthy and unhealthy weight groups, and waist circumference (WC) was compared. Statistical analyses, including Shapiro-Wilk, Student's t-tests, ANOVA, and Results: Forty-three children aged 7-19 years were recruited. Significant differences were observed in liver size and texture between healthy and unhealthy weight groups: RLL length ( Discussion: The findings indicate that large liver and MAFLD are common among children with overweight and obesity, suggesting liver changes related to obesity begin early in life. Strategies to maintain a healthy weight in children are essential to reduce the risk of chronic diseases and potential disabilities in adulthood.

Indexed as

childrenhepatomegalyliver steatosismetabolic-associated fatty liver diseaseobesityoverweightpediatric

Identifiers

PMID40356786
PMCPMC12066509

What Socratic holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.