Evidence map›Paper›PMID 40356822›Full record

ArticleFrontiers in public health2025

A comparative analysis of estrogen receptors, ACE2 and cytokines in pre-and postmenopausal women and men with COVID-19.

Mélida Del Rosario Lizarazo-Taborda, Natali Vega-Magaña, Carlos Daniel Díaz-Palomera, Julio César Villegas-Pineda, Marisol Godínez-Rubí, Rubén Alberto Bayardo-González, Adrián Ramírez-de-Arellano, Ana Laura Pereira-Suárez

Abstract readComparative Study
In one paragraph

Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mélida Del Rosario Lizarazo-TabordaMaestría en Microbiología Médica, Departamento de Microbiología y Patología, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, Mexico.
Natali Vega-MagañaLaboratorio de Investigación en Cáncer e Infecciones, Departamento de Microbiología y Patología, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, Mexico.
Carlos Daniel Díaz-PalomeraLaboratorio de Investigación en Cáncer e Infecciones, Departamento de Microbiología y Patología, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, Mexico.
Julio César Villegas-PinedaLaboratorio de Investigación en Cáncer e Infecciones, Departamento de Microbiología y Patología, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, Mexico.
Marisol Godínez-RubíDepartamento de Morfología, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, Mexico.
Rubén Alberto Bayardo-GonzálezDepartamento de Clínicas Odontológicas Integrales, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, Mexico.
Adrián Ramírez-de-ArellanoLaboratorio de Investigación en Cáncer e Infecciones, Departamento de Microbiología y Patología, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, Mexico.
Ana Laura Pereira-SuárezLaboratorio de Investigación en Cáncer e Infecciones, Departamento de Microbiología y Patología, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, Mexico.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pandemic of Coronavirus Disease 2019 (COVID-19) has a significant impact on older individuals, those with comorbidities, and a bias toward males. Mortality, associated with an exacerbated immune response by proinflammatory cytokines, suggests potential hormonal influences in this scenario. The objective of this research was to analyze the expression of Estrogen Receptor

Indexed as

Angiotensin-Converting Enzyme 2COVID-19CytokinesPostmenopausePremenopauseReceptors, EstrogenAdultAgedEstrogen Receptor alphaFemaleHumansMaleMiddle AgedSARS-CoV-2Viral LoadACE2 protein, humanAngiotensin-Converting Enzyme 2CytokinesEstrogen Receptor alphaReceptors, EstrogenACE2COVID-19estrogen receptorsestrogensSARS-CoV-2

Identifiers

PMID40356822
PMCPMC12066641

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.