Evidence map›Paper›PMID 40356900›Full record

ArticleFrontiers in immunology2025

Cannabidiol and nano-selenium mediate intestinal barrier function by affecting mucosal microstructures, and gut-associated immunological and oxidative stress response in the gut of chickens infected with

Dominika Szkopek, Marta Mendel, Misza Kinsner, Katarzyna Ognik, Natalia Szyryńska, Bogdan Lewczuk, Krzysztof Kozłowski, Ivica Kos, Paweł Konieczka

Abstract read
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Dominika SzkopekDepartment of Animal Nutrition, The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, Jabłonna, Poland.
Marta MendelDivision of Pharmacology and Toxicology, Institute of Veterinary Medicine, Warsaw University of Life Sciences, Warsaw, Poland.
Misza KinsnerDepartment of Animal Nutrition, The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, Jabłonna, Poland.
Katarzyna OgnikDepartment of Biochemistry and Toxicology, Faculty of Animal Sciences and Bio-Economy, University of Life Sciences in Lublin, Lublin, Poland.
Natalia SzyryńskaDepartment of Histology and Embryology, Faculty of Veterinary Medicine, University of Warmia and Mazury, Olsztyn, Poland.
Bogdan LewczukDepartment of Histology and Embryology, Faculty of Veterinary Medicine, University of Warmia and Mazury, Olsztyn, Poland.
Krzysztof KozłowskiDepartment of Poultry Science and Apiculture, University of Warmia and Mazury in Olsztyn, Olsztyn, Poland.
Ivica KosDepartment of Animal Science and Technology, Faculty of Agriculture, University of Zagreb, Zagreb, Croatia.
Paweł KonieczkaDepartment of Animal Nutrition, The Kielanowski Institute of Animal Physiology and Nutrition, Polish Academy of Sciences, Jabłonna, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nutritional additives with biological activity, such as cannabidiol (CBD) and nano-selenium (nano-Se), are viable to prevent bacterial diseases such as necrotic enteritis in chickens. The present study hypothesized that CBD and nano-Se mediate epigenetic and oxidative DNA changes in blood and intestinal epithelial cells and can affect intestinal development and functionality in broiler chickens at an early stage of infection with

Indexed as

CannabidiolClostridium perfringensIntestinal MucosaOxidative StressPoultry DiseasesSeleniumAnimalsChickensDietary SupplementsIntestinal Barrier FunctionCannabidiolSeleniumbroiler chickenscannabidiolC. perfringensDNA changesgut barriernano-seleniumnecrotic enteritis

Identifiers

PMID40356900
PMCPMC12066498

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.