Evidence map›Paper›PMID 40357002›Full record

ArticleScience talks2025

Augmented reality visualization of biomechanical wall stresses on abdominal aortic aneurysms using artificial intelligence.

Timothy K Chung, Pete H Gueldner, Aakash K Kottakota, Christian N Hangey, Jason Y Lee, Nathan L Liang, David A Vorp

Abstract read
In one paragraph

Article in Science talks, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Timothy K ChungDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA.
Pete H GueldnerDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA.
Aakash K KottakotaDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA.
Christian N HangeyDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA.
Jason Y LeeComputational Biology and Bioinformatics, University of Pittsburgh, PA, USA.
Nathan L LiangDepartment of Surgery, University of Pittsburgh, Pittsburgh, PA, USA.
David A VorpDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA.

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR001857 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2016 to 2025
$129.3M
American Heart Association-American Stroke Association 24PRE1195123NCATS NIH HHS UL1 TR001857
6 · The paper itself

Abstract

The number of medical images taken has continued to increase year over year for an aging population in the United States. It has been shown that patients understand their diagnoses better when shown a 2D or 3D image of their respective diseases. However, clinicians do not regularly show patients their images as it requires additional time and processing. In this experiment, we demonstrate the use of augmented reality to visualize abdominal aortic aneurysms using a previously developed artificial intelligence engine. Our group further expanded the number of cases used for training the stress prediction model to a total of 274 patients (206 used for training or ~ 5.4 million nodes, and 68 for testing or ~1.8 million nodes). Medical images undergo automated segmentation, and wall stresses are predicted on the 3D surface of aneurysms to view a heat map. The pipeline includes introducing elements into the Microsoft HoloLens 2 ecosystem to view models and additional analytics, enabling clinicians and patients to view the biomechanical status without the need for a computational or imaging expert. The proposed clinical workflow would allow a local server to process medical imaging data, generate point clouds, predict wall stresses on individual points, and create a 3D model with a colormap to view in augmented reality. The study revealed that neural networks and ensemble boosted tress models predicted the wall stresses more accurately (when compared to ground truth finite element analysis results). The approach is not limited to the HoloLens 2 ecosystem but can be used with other emerging augmented or virtual reality hardware systems.

Indexed as

Abdominal aortic aneurysmsArtificial intelligenceAugmented realityBiomechanicsMetaverseStress analysisVisualization

Identifiers

PMID40357002
PMCPMC12068883

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.