Evidence map›Paper›PMID 40357648›Full record

ArticleNucleic acids research2025

BioPortal: an open community resource for sharing, searching, and utilizing biomedical ontologies.

Jennifer Vendetti, Nomi L Harris, Michael V Dorf, Alex Skrenchuk, J Harry Caufield, Rafael S Gonçalves, John B Graybeal, Harshad Hegde, Timothy Redmond, Christopher J Mungall and 1 more

Abstract read
In one paragraph

Article in Nucleic acids research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. RD-OMICS: An Integrative Multi-Omics Data Inventory in Rare Diseases.bioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. The HuBMAP Framework for Advancing Data FAIRness.bioRxiv : the preprint server for biology · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Large Language Models in Bio-Ontology Research: A Review.Bioengineering (Basel, Switzerland) · 2025
    Review
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jennifer VendettiCenter for Biomedical Informatics Research, Stanford University, Palo Alto, CA 94304, United States.
Nomi L HarrisEnvironmental Genomics and Systems Biology, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, United States.ORCID 0000-0001-6315-3707
Michael V DorfCenter for Biomedical Informatics Research, Stanford University, Palo Alto, CA 94304, United States.
Alex SkrenchukCenter for Biomedical Informatics Research, Stanford University, Palo Alto, CA 94304, United States.
J Harry CaufieldEnvironmental Genomics and Systems Biology, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, United States.ORCID 0000-0001-5705-7831
Rafael S GonçalvesCenter for Biomedical Informatics Research, Stanford University, Palo Alto, CA 94304, United States.
John B GraybealCenter for Biomedical Informatics Research, Stanford University, Palo Alto, CA 94304, United States.
Harshad HegdeEnvironmental Genomics and Systems Biology, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, United States.
Timothy RedmondCenter for Biomedical Informatics Research, Stanford University, Palo Alto, CA 94304, United States.
Christopher J MungallEnvironmental Genomics and Systems Biology, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, United States.ORCID 0000-0002-6601-2165
Mark A MusenCenter for Biomedical Informatics Research, Stanford University, Palo Alto, CA 94304, United States.

Funding

Enhancing the RADx Data Hub for Data FAIRnessOT2DB000009 · OD · STANFORD UNIVERSITY · PI MUSEN, MARK A · 2022 to 2023
$44.3M
BioPortal: An Expansive Knowledgebase of Biomedical Entities and RelationsU24GM143402 · NIGMS · STANFORD UNIVERSITY · PI MUSEN, MARK A · 2021 to 2024
$4.5M
An Intelligent Concept Agent for Assisting with the Application of MetadataU01HG009453 · NHGRI · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI MUNGALL, CHRISTOPHER J · 2016 to 2018
$1.7M
DB NIH HHS OT2 DB000009Department of Energy DE-AC0205CH11231NHGRI NIH HHS U01 HG009453NIGMS NIH HHS U24 GM143402NIH HHS 3OT2DB000009NIH HHS 5U01HG009453-03NIH HHS U24 GM143402
6 · The paper itself

Abstract

BioPortal (https://bioportal.bioontology.org) is the world's most comprehensive repository of biomedical ontologies. It provides infrastructure for finding, sharing, searching, and utilizing biomedical ontologies. Launched in 2005, BioPortal now includes 1549 ontologies (1182 of them public). Its open, freely accessible website enables anyone (i) to browse the ontology library, (ii) to search for terms across ontologies, (iii) to browse mappings between terms, (iv) to see popularity ratings and recommendations on which ontologies are most relevant to their use cases, (v) to annotate text with ontology terms, (vi) to submit an ontology, and (vii) to request ontology changes. The library of ontologies can be accessed programmatically via a REST application programming interface (API). Recent enhancements include a BioPortal knowledge graph that integrates knowledge from multiple ontologies; a unified data model for interoperability with other knowledge sources; ontology popularity ratings and recommendations for relevant ontologies; and the ability to request ontology changes via a simple user interface that automatically converts user change requests to GitHub Pull Requests that specify the edits that will be made to the ontology upon approval.

Indexed as

Biological OntologiesDatabases, FactualHumansInformation DisseminationInternetSoftwareUser-Computer Interface

Identifiers

PMID40357648
PMCPMC12230712

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.