Evidence mapPaperPMID 40357683Full record

ReviewCurrent opinion in rheumatology2025

Cardiovascular disease risk in psoriatic disease: mechanisms and implications for clinical practice.

John L Medamana, Joel M Gelfand, Brittany N Weber, Michael S Garshick

Abstract readReview
In one paragraph

Review in Current opinion in rheumatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

John L MedamanaLeon H. Charney Division of Cardiology, Department of Medicine, New York University School of Medicine, New York, New York.
Joel M GelfandDepartment of Dermatology and Department of Biostatistics, Epidemiology, and Informatics, Center for Clinical Sciences in Dermatology, University of Pennsylvania Perelman School of Medicine, Philadelphia.
Brittany N WeberHeart and Vascular Center, Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.
Michael S GarshickLeon H. Charney Division of Cardiology, Department of Medicine, New York University School of Medicine, New York, New York.

Funding

Endovascular Health and Platelet Activity in PsoriasisK23HL152013 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · 2023 to 2025
$345k
Advanced CV imaging and immunophenotyping to study coronary vascular health in psoriasisK23HL159276 · UT SOUTHWESTERN MEDICAL CENTER · 2025 to 2025
$194k
NHLBI NIH HHS K23 HL152013NHLBI NIH HHS K23 HL159276
6 · The paper itself

Abstract

purpose of reviewPsoriasis is an immune-mediated pro-inflammatory skin condition that is associated with an increase in risk factors for cardiovascular disease, risk of ischemic heart disease, and cardiovascular death. Despite this, traditional modifiable atherosclerotic cardiovascular disease (ASCVD) risk factors are underdiagnosed and undertreated in patients with psoriasis. RECENT

findingsAt a cellular level, psoriasis and atherosclerosis are driven by a host of shared inflammatory pathways, such as pro-inflammatory cytokines (TNF, IL-6), immune cells, and platelets which act synergistically to drive endothelial damage and atherosclerosis progression. SUMMARY: Optimal prevention of cardiovascular disease in psoriasis centers around modifying known risk factors for the development of ASCVD and emerging data highlight the promise of treating inflammation to further decrease the risk of ASCVD.

Indexed as

Cardiovascular DiseasesPsoriasisAtherosclerosisHeart Disease Risk FactorsHumansInflammationRisk Factorsatherosclerosisinflammationpsoriasis

Identifiers

PMID40357683
PMCPMC12167429

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.