ArticleThe journal of headache and pain2025
Burden of migraine among Egyptian people: prevalence and comorbidities.
Article in The journal of headache and pain, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Mechanistic Overlaps Between Sleep and Headache Disorders: From Dopaminergic Dysfunction to Neuroinflammation-A Narrative Review.Clocks & sleep · 2026Review
- Real-world assessment of current migraine prophylaxis in Egypt: a multicenter national study.The journal of headache and pain · 2026Article
- Efficacy, tolerability and barriers to the use of anti-CGRP medications among migraine patients in Egypt: real world experience.Frontiers in neurology · 2026Article
- Headache service quality in Egypt: current status, identified gaps, and strategic directions.Frontiers in neurology · 2026Article
- Impact of bariatric surgery on headache frequency and severity and quality of life in patients with migraine: a prospective study.BMJ neurology open · 2026Article
- Migraine with comorbid fibromyalgia: psychological burden and impact on frequency and severity of migraine attacks.Frontiers in neurology · 2026Article
- Burden of migraine among university students in the Middle East and North Africa: a cross-sectional study of prevalence, mental health comorbidities, and disability.BMC public health · 2025Article
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10 authors.
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Abstract
introductionMigraine is a prevalent debilitating neurological illness that stands among the top causes of disability and significantly impacts the quality of life. Migraine-related functional impairment involves physical, emotional, and economic consequences that frequently impact occupational, academic, social, and familial aspects of life. Depression, anxiety, and sleep disturbances are among the most common comorbid conditions associated with migraine.
objectiveThis study aimed to assess the prevalence of migraine among the Egyptian population and associated comorbidities.
methodswe conducted a cross-sectional study using a validated Arabic self-administered questionnaire distributed to the general population. The questionnaire was used to collect data on sociodemographic characteristics, migraine frequency, characteristic associated disability, insomnia, and psychological factors. Convenience snowball sampling method was utilized. Univariate and multivariate regression analyzes were applied.
resultsA total of 2,533 participants were included in the final analysis from five Egyptian regions. Females represent 57%. More than one-half of participants (59.1%) aged 20-30 years. The prevalence of migraine was 20.9%. The most common triggers were sleep disorders (76.9%), followed by perceived noise (65%), and anxiety (59%). Among the participants diagnosed with migraine, 46.7% had a severe disability, 22% had clinical insomnia of moderate severity, 20.5% had severe depression, 29% had severe anxiety, and 20.6% had severe stress. Females, older age, and urban residents were the key predictors of migraine. Lifestyle factors including regular physical activity and good hydration were linked to reduced migraine risk. Comorbid conditions including insomnia, stress, and anxiety significantly impacted migraine severity.
conclusionOur results showed a 20.9% prevalence of migraine, with nearly one-half of cases associated with severe disability, along with comorbidities like depression, anxiety, and insomnia. Female gender, older age, and urban residence are key predictors, while lifestyle factors such as physical exercise and good hydration reduce the risk of migraine.
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