Evidence map›Paper›PMID 40362337›Full record

ReviewInternational journal of molecular sciences2025

The Importance of Mitochondrial Processes in the Maturation and Acquisition of Competences of Oocytes and Embryo Culture.

Elżbieta Gałęska, Alicja Kowalczyk, Marcjanna Wrzecińska, Mercedes Camiña García, Ewa Czerniawska-Piątkowska, Szymon Gwoździewicz, Wojciech Witkiewicz, Zbigniew Dobrzański

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

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  12. Oxidative Stress andInternational journal of molecular sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Elżbieta GałęskaDepartment of Environment Hygiene and Animal Welfare, Wrocław University of Environmental and Life Sciences, 51-630 Wrocław, Poland.
Alicja KowalczykDepartment of Environment Hygiene and Animal Welfare, Wrocław University of Environmental and Life Sciences, 51-630 Wrocław, Poland.ORCID 0000-0003-1908-2942
Marcjanna WrzecińskaDepartment of Environment Hygiene and Animal Welfare, Wrocław University of Environmental and Life Sciences, 51-630 Wrocław, Poland.ORCID 0000-0002-3529-8404
Mercedes Camiña GarcíaDepartment of Physiology, University of Santiago de Compostela, 15705 Santiago de Compostela, Spain.ORCID 0000-0002-0179-7280
Ewa Czerniawska-PiątkowskaDepartment of Ruminant Science, West Pomeranian University of Technology in Szczecin, 70-310 Szczecin, Poland.
Szymon GwoździewiczInstitute of Animal Breeding, Wrocław University of Environmental and Life Sciences, 51-630 Wrocław, Poland.
Wojciech WitkiewiczResearch and Development Center, Voivodeship Specialist Hospital in Wrocław, 51-124 Wrocław, Poland.
Zbigniew DobrzańskiDepartment of Environment Hygiene and Animal Welfare, Wrocław University of Environmental and Life Sciences, 51-630 Wrocław, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitochondria, as multifunctional and partially independent structures, play a crucial role in determining essential life processes. Recently, their significance in reproductive biology has gained increasing attention. This review aims to comprehensively analyse the role of mitochondrial processes in oocyte maturation and embryo culture. A comprehensive literature review was conducted to highlight the importance of mitochondrial activity in the early stages of life formation. Proper mitochondrial function provides energy, maintains genomic stability, and ensures optimal conditions for fertilisation and embryo progression. Understanding these processes is essential to optimise culture conditions and identify new mitochondrial biomarkers that improve reproductive success and improve assisted reproductive technologies (ARTs). Enhancing mitochondrial function in female reproductive cells is the key to improving oocyte and embryo quality, which can lead to better in vitro fertilisation and embryo transfer. Furthermore, advances in diagnostic techniques, such as mitochondrial genome sequencing, offer a more precise understanding of the relationship between mitochondrial health and oocyte quality. However, fully understanding mitochondrial functions is only part of the challenge. Expanding knowledge of the interactions between mitochondria and other cellular structures is crucial for future advancements in reproductive medicine. Understanding these complex relationships will provide deeper insight into improving reproductive outcomes and embryo development.

Indexed as

Embryo Culture TechniquesMitochondriaOocytesAnimalsEmbryonic DevelopmentFemaleHumansembryo culturematurationmitochondriaoocytesreproduction

Identifiers

PMID40362337
PMCPMC12071309

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.